No abstract

A Serra dos Tapes, região ao sul do Rio Grande do Sul que compreende, entre outros, os municípios de Pelotas, São Lourenço do Sul e Canguçu, é habitada por grupos camponeses de diferentes origens e identidades étnicas, cujos modos de vida são aqui abordados tendo a comida e a imagem como objetos, símbolos e instrumentos de partilha, mediação e diálogo da agenda de pesquisa "Saberes e Sabores da Colônia". Conduzida pelo

L'agglomération d'Elne, dont la localisation date seulement du début des années 1950, a fait l'objet de nouvelles recherches depuis la fin des années 1990. Ces dernières ont donné lieu à la publication de plusieurs synthèses sur l'occupation, affinant notamment notre connaissance en terme de chronologie et d'espace. Toutefois, de nombreux domaines étaient restés en suspens faute d'éléments probants, notamment sur l'existence d'un système de défense autour de la ville. La fouille récente d'un tronçon de fossé du deuxième âge du Fer a permis d'apporter des éléments de réflexion décisifs dans ce domaine, permettant une nouvelle interprétation de certaines découvertes anciennes. D'autre part, la richesse relative et la variété du mobilier découvert lors de cette fouille a permis de mener plusieurs études complémentaires, en particulier céramologique, carpologique et anthracologique complétant ainsi assez considérablement ces domaines encore peu explorés en Roussillon.

No abstract

BackgroundTo describe the long term outcome of patients who interrupted highly active antiretroviral therapy (HAART) once, identify the variables associated with earlier need to re-start HAART, and the response when therapy was resumed. A retrospective observational cohort of 66 adult patients with HIV-1 infection who interrupted HAART with a CD4+cell count ≥350 cells/μL and undetectable viral load (VL) was performed. The pre-established CD4+ cell count for restarting therapy was 300cells/μL. Cox regression was used to analyse the variables associated with earlier HAART reinitiation.ResultsThe median follow-up was 209 weeks (range, 64–395). Rates of HIV-related or possible HIV-related events were 0.37 (one case of acute retroviral syndrome) and 1.49 per 100 patient-years, respectively. Two patients died after re-starting therapy and having reached undetectable VL. Three patients suffered a sexually transmitted disease while off therapy. Fifty patients (76%) resumed therapy after a median of 97 weeks (range, 17–267). Age, a nadir of CD4+ <250 cells/μL, and a mean VL during interruption of >10,000 copies/ml were independent predictors for earlier re-start. The intention-to-treat success rate of the first HAART resumed regimen was 85.4%. There were no differences by regimen used, nor between regimens that were the same as or different from the one that had been interrupted.ConclusionsOur data suggest highly active antiretroviral therapy may be interrupted in selected patients because in these patients, when the HAART is restarted, the viral and clinical response may be achieved.