A rare case report of periodontal disease associated with familial benign chronic neutropenia is presented. The medical, dental and family histories as well as clinical and histologic observations are described and discussed.

A new model system for inducing reaginic antibody formation in mice is presented, namely a single injection of rabbit anti-mouse thymocyte serum (RAMTS). Using this model we have shown that X-irradiation (450 rad) administered to CBA mice 24 h after a single injection of RAMTS or IgG- (RAMTS) results in a sustained moderately high level of reagins against rabbit serum proteins with a concomitant barely detectable level (titer 1:5) of γ₁-antibodies. Splenectomy and thymectomy had no demonstrable effect on reaginic antibody synthesis.

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The device consists of a tube with a conical end, a base, and a movable stem. The rodent is anaesthetized lightly with ether and inserted quickly into the tube so that the head extends beyond the opening at the conical end, where cheeks, upper and lower incisors are secured to permit illumination and direct visual or microscopic examination of the palate, molars or gingiva.