Microfluidic chip technology is an emerging tool in the field of biomedical application. Microfluidic chip includes a set of groves or microchannels that are engraved on different materials (glass, silicon, or polymers such as polydimethylsiloxane or PDMS, polymethylmethacrylate or PMMA). The microchannels forming the microfluidic chip are interconnected with each other for desired results. This organization of microchannels trapped into the microfluidic chip is associated with the outside by inputs and outputs penetrating through the chip, as an interface between the macro- and miniature world. With the help of a pump and a chip, microfluidic chip helps to determine the behavioral change of the microfluids. Inside the chip, there are microfluidic channels that permit the processing of the fluid, for example, blending and physicochemical responses. Microfluidic chip has numerous points of interest including lesser time and reagent utilization and alongside this, it can execute numerous activities simultaneously. The miniatured size of the chip fastens the reaction as the surface area increases. It is utilized in different biomedical applications such as food safety sensing, peptide analysis, tissue engineering, medical diagnosis, DNA purification, PCR activity, pregnancy, and glucose estimation. In the present study, the design of various microfluidic chips has been discussed along with their biomedical applications.
A study of the weathering of micaceous clays in some Norwegian podzols, includes semiquantitative estimates of minerals in the concentrated clay fractions which show a decrease in the amounts of illite and chlorite, and an increase in vermiculite and mixed-layer minerals upward in the profile. Illite, the dominant mineral at depth, weathers to hydrobiotite in the surface horizon of the profile. Subsequent weathering of hydrobiotite in this portion of the profile produces trioctahedral vermiculite and smectite, or intergrade smectite-chlorite.
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