Edwardsiellosis is one of the most important bacterial diseases in fish. Scientific work on this disease started more than forty years ago and numerous workers around the world are continually adding to the knowledge of the disease. In spite of this, not a single article that reviews the enormous scientific data thus generated is available in the English language. This article briefly discusses some of the recent research on edwardsiellosis, describing the pathogen's interaction with the host and environment, its pathogenesis and pathology as well as diagnostic, preventive and control measures.

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The study was undertaken to determine the modulation in innate immune response of rohu (Labeo rohita) during experimental freshwater lice Argulus siamensis infection. Results showed that serum a-2 macroglobulin (a-2M) activity, ceruloplasmin level and alternative complement activity were signi¢cantly (Po0.05) lower in ¢sh at di¡erent degrees of lice infection in comparison with uninfected control. No signi¢cant di¡erence (P40.05) in haemagglutination titre was observed in ¢sh with low-and high-degree lice infections as compared with uninfected control. The serum lysozyme level was signi¢cantly (Po0.05) lower in low degree of lice infection as compared with control ¢sh. The total serum antiprotease, myeloperoxidase activity and total protein level were not signi¢cantly di¡erent (P40.05) in di¡erent degrees of lice-infected ¢sh with respect to the control ¢sh. The study indicated that A. siamensis infection modulated the immune system of rohu by suppressing the a-2M, serum complement activities and ceruloplasmin level and through induction of stress response. The baseline data obtained in the present study have tremendous importance in understanding the susceptibility of rohu to di¡erent degrees of parasitosis and might be useful in controlling this dreaded ectoparasitic infection in ¢sh.