No abstract

The technique proved easy to perform, safe, and effective.

The objective of the present study was to assess the treatment of dogs with ehrlichiosis (tropical canine pancytopenia (TCP)) with doxycycline hydrochloride associated or not with prednisolone on the hematological profile and serum proteins. Ten dogs with TCP were selected in the Small Animal Medical Clinic Veterinary Hospital, Federal University of Campina Grande-UFCG-PB, Brazil. The diagnosis was obtained by clinical examination, hemogram and immunochromatographic test (with anti Ehrlichia canis antibodies). Samples were distributed randomly in two experimental groups of five animals each (n = 5), named GD and GDP. The GD group was treated with doxycycline (5 mg/kg, VO, BID for 28 days) and the GDP group was treated with doxycycline at the same dose and duration and prednisolone (2 mg/kg, VO, BID, for five days). Four blood collections were made during the treatment period: a base collection (M0), one at 10 days (M10), a second at 21 days (M21) and another at the end of the treatment (M28). These samples were used for the tests erythrogram, leucogram, plateletgram and proteinogram (dose of total proteins, pre-albumin, albumin, albumin, α-1 globulin, α-2 globulin, ß-globulin, ɣ-globulin and C- reactive protein) in the Clinical Pathology Laboratory, Veterinary Hospital-UFCG-PB. Results, that presented normal distribution, was submitted to the Tukey test (P<0.05). Comparison of treatments GD and GDP showed that both promoted discreet and similar response in the hematological parameters at different times. Results obtained allowed the conclusion that both therapeutic protocols resulted in clinical, hematological parameter and proteinogram improvement, but the use of prednisolone at the dose administered during the first five days of treatment did not show more beneficial effects than isolated administration of doxycycline.

Presença de Leishmania spp. na conjuntiva de um cão não reativo para testes parasitológicos em linfonodos e medula óssea -relato de casoPresence of Leishmania spp. in the conjunctive of a nonreactive dog for parasitological tests in lymphonod and bone marrow -case report A B S T R A C TThe objective of this work was to report the detection of amastigote forms of Leishmania spp.through conjunctival cytology in a non-positive dog for parasitological tests in bone marrow, popliteal lymph nodes and right and left superficial cervicals. A female dog a was attended to with a history of skin problems and dry cough was seen five years ago. After clinical evaluation were performed a cytology of bone marrow, popliteal lymph nodes and superficial cervical, being these negative for parasites. Therefore, new cytological samples were collected in the right and left palpebral conjunctival regions, with the presence of amastigotes of Leishmania spp. It is still unclear to scholars how the amastigote forms of this parasite reach into the ocular tissues, although some of them believe that the parasites are carried by the antigen-presenting cells. It was concluded that conjunctival cytology was a complementary method of diagnosis of leishmaniasis in a non-reactive dog for direct parasitological examination in the medullary and lymph node sites. . Universidade Federal de Campina Grande R E S U M OObjetivou-se com este trabalho relatar a detecção de formas amastigotas de Leishmania spp. através de citologia conjuntival em um cão não positivo para testes parasitológicos em medula óssea, linfonodos poplíteos e cervicais superficial direito e esquerdo. Foi atendida uma cadela com histórico de problemas de pele e tosse seca há cinco anos. Após avaliação clínica, realizouse citologia de medula óssea, linfonodos poplíteos e cervicais superficiais, sendo estes negativos para parasitas. Diante disso, coletou-se novas amostras citológicas na região de conjuntiva palpebral direita e esquerda, sendo nestas observadas formas amastigotas de Leishmania spp. Ainda é uma incógnita para os estudiosos como as formas amastigotas desse parasita chegam aos tecidos oculares, embora alguns deles acreditem que os parasitas são transportados pelas células apresentadoras de antígeno. Conclui-se que a citologia conjuntival foi um método complementar de diagnóstico de leishmaniose em um cão não reativo para exame parasitológico direto em sítio medular e de linfonodo. K E Y W O R D SOphthalmology. Leishmaniasis. Cytology. Conjunctivitis.

O Condrossarcoma (CSA) é um tumor mesenquimal, normalmente de crescimento lento, bem diferenciados e com baixa taxa de metástase. Sua sintomatologia varia de acordo com o tamanho do tumor e a área afetada, podendo haver aspectos como massa palpável assintomática. O diagnóstico é embasado na anamnese, exames físicos, exames laboratoriais, radiografia tradicional, tomografia computadorizada (TC), ressonância magnética (RM), citologia e exames histopatológicos. A cirurgia é a principal forma de tratamento, sendo o princípio básico a ressecção com amplas margens de segurança, pois a recidiva é um dos fatores de mau prognóstico. A prevalência é maior em cães de raças de médio e grande porte, sendo raro em cães de raça pequena e gigantes. Na Medicina Veterinária, o condrossarcoma extraesquelético é um tumor raro de tecido mole. Esse relato descreve o caso de cão da raça Shih-tzu que foi atendido no Hospital Veterinário Harmony Vet, Natal/RN, no qual o paciente apresentava sinais recorrentes de obstrução urinária e após realização de ultrassonografia e tomografia computadorizada foi constatada a presença de um nódulo na transição entre uretra perineal e uretra peniana. O tratamento foi realizado com a cirurgia de penectomia total e uretrostomia. A histopatologia do nódulo revelou condrossarcoma pouco diferenciado. No período de 6 meses após a cirurgia, o animal teve uma piora por causa do nódulo pulmonar e foi realizada a eutanásia do paciente.

RESUMO: O conhecimento clínico das alterações cardíacas em cães é de fundamental importância na formulação de diagnósticos diferenciais e instituição terapêutica na rotina da Clínica Médica de Pequenos Animais. Objetivaram-se com este estudo descrever os aspectos clínicos, epidemiológicos e radiográficos inerentes as alterações cardiovasculares de cães cardiopatas atendidos no Hospital Veterinário de Patos-PB (HV). Para isso foram avaliados os prontuários clínicos de todos os animais atendidos no período de Janeiro de 2007 a Dezembro de 2012, selecionando-se 131 cães (GCARD) que apresentavam histórico, alterações clínicas e radiográficas compatíveis com cardiopatia. Para fins comparativos, um grupo controle sem cardiopatia de igual número foi criado (GCON). Para análise estatística foram utilizados o teste de qui-quadrado ou teste exato de Fisher e regressão logística múltipla, com nível de significância de 5%, utilizando-se o programa SPSS 20.0 for Windows. Edema pulmonar e alterações morfológicas cardíacas foram os achados radiográficos mais frequentes. Não houve diferença quanto ao sexo e prevaleceram os animais mais velhos e da raça poodle. Tosse, cansaço e tristeza foram as queixas mais comuns. Sopro, tártaro e alterações oculares foram os sinais clínicos de maior ocorrência. As variáveis relacionadas ao engasgo, tontura/fraqueza, creptação pulmonar, ascite, obesidade, tumor e tártaro foram identificadas como associadas às cardiopatias. O modelo final apresentou ajuste satisfatório (teste de Hosmer e Lemeshow: χ2=0,221; P=0,994; R2 = 0,46). Mesmo que não seja possível determinar o diagnóstico etiológico das cardiopatias, faz-se necessário que um amplo conhecimento clínico e epidemiológico destes seja cada vez mais consolidado, de modo que as consequências fisiopatológicas dos distúrbios cardíacos sejam rapidamente identificados, trazendo qualidade de vida a todos os pacientes cardiopatas.

Background: Several treatments for oral papillomatosis in dogs, with satisfactory results, have already been described in the literature. However, there is need for further studies regarding remission time, association and exposure to drugs, side effects, cost-effectiveness and reproducibility of results. Autohemotherapy (AHT) is a therapeutic technique increasingly used in veterinary medicine that has been providing satisfactory clinical results to treat several pathologies. The procedure consists of removing blood by intravenous puncture that is immediately re-administered via intramuscular, subcutaneous, intravenous or intradermal. Although the empirical isolated use via intramuscular reached excellent results in routine medical treatment of dogs and since few studies and protocols have been described for this species, many times the treatment is based on the experience with the bovine papillomatosis. To this end, this report describes a case of canine oral papillomatosis treated with autohemotherapy (AHT), emphasizing the dosage and clinical evolution of the case.Case: A one-year-old mongrel dog rescued from the street eight months earlier was treated. The animal was thin resulting from the small food amount ingested due to feeding difficulty, infested with ticks, had bad breath and few small warts on the lips, which, after five months, grew and multiplied, and were distributed throughout the oral cavity. The animal clinical history led to papillomatosis diagnosis, which was confirmed by cytological and histopathological exams. The AHT treatment consisted of taking 5 mL of whole blood without EDTA and immediately injecting this volume intramuscularly, every four days until the total remission of the clinical symptoms. Every four days, the papilloma fall off, and involution processes were recorded through a detailed macroscopic analysis of the warts (quantity, consistency, color and size), as well as hematological evaluations (blood count, hemoparasite screening and total plasm protein), which were performed before each AHT treatment until the complete clinical resolution of the disease (24 days).Discussion: The dose adopted in this autohemotherapy study was clinically effective since the papillomas started to fall off after four days of therapy, with total resolution in 24 days. Therefore, it can be concluded that the 5 mL AHT injected intramuscularly every four days reduced treatment time and decreased therapeutic costs. There are few studies evaluating more accurately the hematological aspects related to the therapeutic use of autohemotherapy to treat canine oral papillomatosis, the existing reports are restricted to the initial measurement as an evaluation of the general condition of the patient and/or diagnosis of possible basal diseases. In this study, no changes were observed in the blood count during the entire therapeutic process, demonstrating that the AHT did not interfere in the red series dynamics of the treated animal. Additionally, thrombocytosis followed by thrombocytopenia exhibited a correlation with the macroscopic appearance of warts [enlargement and modified color, texture, shape and consistency]. This observation is possibly related to a platelet mobilization toward the site of action [warts], so that there was a modulation in the immune response, amplifying the inflammatory process and tissue repair, which resulted in the fall off and involution of the papillomas.