2021
DOI: 10.1590/0103-8478cr20200335
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Prednisolone associated with doxycycline on the hematological parameters and serum proteinogram of dogs with ehrlichiosis

Abstract: The objective of the present study was to assess the treatment of dogs with ehrlichiosis (tropical canine pancytopenia (TCP)) with doxycycline hydrochloride associated or not with prednisolone on the hematological profile and serum proteins. Ten dogs with TCP were selected in the Small Animal Medical Clinic Veterinary Hospital, Federal University of Campina Grande-UFCG-PB, Brazil. The diagnosis was obtained by clinical examination, hemogram and immunochromatographic test (with anti Ehrlichia canis antibodies).… Show more

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“…Regarding thrombocytopenia in infected dogs with E. canis , it is a very common alteration described in CME [ 38 ]. The use of doxycycline, in addition to the antimicrobial effect on E. canis [ 39 ], has a specific effect on platelet proliferation [ 37 ]. This description was shown in our study by the increase in platelets in the group of dogs with treatment, an effect also reported in other studies [ 37 , 40 ].…”
Section: Discussionmentioning
confidence: 99%
“…Regarding thrombocytopenia in infected dogs with E. canis , it is a very common alteration described in CME [ 38 ]. The use of doxycycline, in addition to the antimicrobial effect on E. canis [ 39 ], has a specific effect on platelet proliferation [ 37 ]. This description was shown in our study by the increase in platelets in the group of dogs with treatment, an effect also reported in other studies [ 37 , 40 ].…”
Section: Discussionmentioning
confidence: 99%