Relevance: Breast cancer is one of the most common malignancies with a high mortality rate all over the world, including Kazakhstan. Despite modern advanced diagnosis and treatment methods, breast cancer remains one of the top three «killer cancers.» Treatment with immunoglobulins and modern targeted chemotherapy agents is efficient but does not reduce the breast cancer incidence. High treatment cost, antitumor drug resistance occurring during therapy, and significant side effects of chemotherapy urge the importance of prophylactic actions able to prevent the tumor disease. Purpose: To review the Vitamin D3 role and potential in breast cancer prevention. Results: The analysis of the literature reviews and original articles accessing the Vitamin D3 role in breast cancer pathogenesis and the study of the main antitumor mechanisms of Vitamin D3 action emphasize the need for large randomized prospective studies to determine the actual Vitamin D3 role in breast cancer pathogenesis and its possible inclusion in antitumor therapy regimens. Conclusion: The results obtained evidence the Vitamin D3 adjuvant potential in breast cancer treatment
Breast cancer is one of the most common malignancies with a high mortality rate worldwide, including in Kazakhstan. Despite modern advanced di-agnosis and treatment methods, breast cancer remains one of the top three “killer cancers.” Treatment with immunoglobulins and modern targeted chemotherapy agents is efficient but does not reduce breast cancer incidence. High treatment cost, antitumor drug resistance occurring during therapy, and significant side ef-fects of chemotherapy urge the importance of prophylactic actions to prevent the tumor disease. The purpose of the study was to review the Vitamin D3 role and potential in breast cancer prevention. Results: The analysis of the literature reviews and original articles accessing the Vitamin D3 role in breast cancer pathogenesis and the study of the main anti-tumor mechanisms of Vitamin D3 action emphasize the need for large randomized prospective studies to determine the actual Vitamin D3 role in breast cancer pathogenesis and its possible inclusion in antitumor therapy regimens. Conclusion: The results obtained evidence on the Vitamin D3 adjuvant potential in breast cancer treatment.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.