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Background:Prevalence of diabetes is on an increase in India, currently there is limited nation-wide data regarding the prevalence of chronic complications in diabetic patients at diagnosis. This information will help health-care professionals approach management more aggressively to prevent complications.Objective:To determine the prevalence of chronic complications in newly-diagnosed Type 2 diabetic (T2D) patients in India.Design and Methods:This was a cross-sectional survey of T2D patients, diagnosed within 3 months of their first visit to the centers doing the survey. Each patient was screened for diabetic complications, hypertension, dyslipidemia, and body mass index. Family history was recorded. Standard protocols were used to make the diagnosis of retinopathy, neuropathy and nephropathy. Data analysis was carried out using the standard statistical techniques.Results:Of the total 4,600 (males 67%, females 33%) newly diagnosed patients with T2D, majority were from the age group 41-50 years (40%). 13.15% of newly detected India T2D had neuropathy 6.1% had retinopathy and 1.06% had nephropathy. Risk factors of macro vascular complication such as hypertension, obesity, and dyslipidemia were observed in 23.3%, 26%, and 27% of patients respectively. Ischemic heart disease was noticed in 6%.Conclusion:High prevalence of micro vascular complications was present at diagnosis along with association of CV cardiovascular risk factors among Indian T2D. In view of this, screening must be instituted for all diabetics for complications at the time of diagnosis itself.

Background:Women with gestational diabetes mellitus (GDM) pose an important public health problem because diabetes not only affects the maternal and fetal outcome, but these women and their fetuses are also at an increased risk of developing diabetes and related complications later in their life.Objectives:The study was conducted to determine the maternal and fetal outcomes of 50 diabetic vs 50 normoglycemic pregnancies.Materials and Methods:This was a retrospective analytical record-based study conducted in a tertiary level hospital. Detailed information regarding maternal, fetal, and labor outcome parameters was recorded in a prestructured proforma and compared in normoglycemic and diabetic pregnancies.Results:Patients with obesity, history of diabetes in the family, spontaneous abortions, and gestational diabetes in previous pregnancies had a greater incidence of GDM in current pregnancy (P<0.05 for all). Hypertension, polyhydramnios, macrosomia, fetopelvic disproportion, and cesarean sections were more (P<0.001) among diabetic pregnancies. Congenital anomalies, polycythemia, hypocalcemia, and hyperbilirubinemia were also observed to be more (P<0.05) in neonates born to diabetics, suggesting an adverse effect of hyperglycemia in utero.Conclusion:Diabetes during pregnancy is associated with higher maternal and fetal morbidity. Therefore, early screening, detection, close monitoring, and intervention is essential to reduce maternal and fetal short- and long-term adverse effects, especially in high-risk groups. Pregnancy provides an opportunity to the clinician to control the disease process and inculcate healthy lifestyle practices in these patients.

Many physiological hematological changes occur during pregnancy to accommodate the demands of the developing foetus. Infect, these changes may appear to be pathological in the non-pregnant state. Although physiological in nature, but abnormal hematological profile does affect pregnancy and its outcome. One of the most important underlying cause of maternal mortality is due to underlying hematological complications. This review deals with thorough understanding of range of these haematological parameters during pregnancy.

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Purpose: This study was performed to study the pattern of fluoride release from glass ionomer cement, a resin modified glass ionomer cement, a compomer and a composite resin when stored in different storage media.Methods: A total of 60 samples (Tablets of diameter 8.6 ± 0.1 mm and thickness 1.65 ± 0.1 mm) were prepared (15 samples for each material) pertaining to 4 different materials used. Five samples of each material were suspended in 4 ml of each studied solution. The studied media were deionized water, artificial saliva and solutions for pH-cycling (demineralizing solution pH 4.3 and remineralizing solution pH 7.0). The total experimental period was fifteen days the readings were taken after day 1, day 2, day 5, day 9 and day 15 using ORION fluoride ion specific electrode.Results: Significant variations were found in the amount of fluoride release from all the materials in different storage media.Glass ionomer cement released significantly higher amounts of fluoride (p < 0.001) in all storage media. The difference between composite resin and other materials was also very significant (p 0.001) where composite resin released very less fluoride in all the media.Conclusion: From this study it was concluded that the greatest amount of fluoride release was from ART glass ionomer cement in all the media followed by resin modified glass ionomer cement, compomer and composite resin in decreasing order. The pattern of fluoride release was similar for all the examined materials.Maximum amount of fluoride release was observed in pH cycling model for all the materials followed by deionized water and artificial saliva in decreasing order. With this it can be concluded that pH strongly affects fluoride release from dental restorative materials.

The study shows that awareness of PPIUCD is low in this region despite good education, leading to high refusal rates. The commonest reason is lack of appropriate counseling, and not only the woman but the husband and mother-in-law also must be provided the knowledge of it as they play important roles in our society.