A decrease in cholinesterase (chE) enzyme activity is an indicator of pesticide poisoning, especially organophosphate pesticides. The chE activity reduction will result in an increase in the amount of acetylcholine and will bound to muscarinic and nicotinic receptors in the central and peripheral nervous system which can lead to the onset of Alzheimer's disease. However, antioxidant products can slow the progression of Alzheimer's disease by protecting neurons from oxidative stress. Red Beetroot (Beta vulgaris L.) contains betalains and phenolic compounds which act as an antioxidants that are capable of preventing such illness. This study aims to prove the concept that antioxidant compounds in red beetroot juice can increase the chE activity in subjects exposed to organophosphate pesticides. This research is an observational study with an experimental approach. This research used 25 farmers who were exposed to organophosphate pesticides as respondents. They were given 500 ml of beetroot juice twice a day for 2 consecutive months. Cholinesterase levels were measured before and after consuming red beet juice. Measurement of cholinesterase levels was carried out using a kinetic photometric test. This method was developed based on recommendations from the German Society of Clinical Chemistry (DGKC). The results showed that the average of chE (U/L) Level Before Treatment was 8.102 and 8.380 after treatment with a p value 0,62. It can be concluded that there was an increase in the level of cholinesterase but it was not statistically significant. This may be caused by a different response to activity of cholinesterase after consuming beetroot juice in each subjects, age difference, smoking habits, and personal protective equipment.
Most pregnant women give birth normally, but 15% of cases are life-threatening complications including preeclampsia. Preeclampsia is marked by an increase in proteinuria, whereas protein is closely related to leukocytes because the breakdown of proteins into amino acids is carried out by enzymes present in leukocytes, especially neutrophil cells. This study aims to determine the relationship between urine leukocyte levels and protein in urine in third trimester pregnant women. The research design used was analytic observation with a cross sectional approach. The study population was 35 Trimester III pregnant women in Madura klampis puskesmas, then determined based on the formula Slovin found 31 Trimester III pregnant women. The sampling technique is done using probability sampling technique. The results of research conducted based on the chi square test showed that the significance of p> 0.05 was 0.111 which showed that there was no relationship between leukocytes and urine protein in third trimester pregnant women.
The incidence of anemia is common in adolescent girls. Anemia causes decreased learning achievement due to lack of concentration. This research aimed to analyze the determinant factors associated with the incidence of anemia in female students at Islamic Boarding School Al Hidayah 2 Bangkalan. The research was observational analytic, a cross sectional design. The population was female students at Islamic Boarding School Al Hidayah 2 and the sample size was 72 people. The independent variables include menstrual patterns, sleep patterns, consumption patterns of food sources of iron and nutritional status. The dependent variable was anemia status. Data collection on menstrual patterns and sleep patterns used a questionnaire, consumption patterns with the Food Frequency Questionnaire and anemia status by testing hemoglobin levels. Analysis of the data by Contingency Coefficient test. The results showed that 27.8% of subjects experienced menorrhagia, 54.2% had poor sleep patterns, 58.3% had good food consumption patterns, 25.0% had underweight nutritional status, and 13.9% subjects experienced anemia. Correlation tests showed that the menstrual pattern was significantly related to anemia status (p=0.048). Sleep pattern (p=0.776), food consumption pattern (p=0.908) and nutritional status (p=0.462) were not significantly correlated with the incidence of anemia. Menstrual pattern is the most influential factor of anemia incidence. The longer of menstrual period will cause the greater the chance of the subject experiencing anemia.
Introduction: Diabetes mellitus (DM) is a serious threat to human health in the 21st century, Indonesia as a developing country has a high number of sufferers. This study aims to analyze the effect of discharge planning on the stability of blood sugar levels in type 2 patients. Methods: The design of this study was a Quasi-Experimental Pre and Post-test with a Control Group. The population in this study were all patients with type 2 DM, a large sample of 54 respondents, taken by purposive sampling technique. The instruments used are a glucometer, questionnaire, and discharge planning form. Data analysis used Wilcoxon statistical test for pre-treatment and control groups and the Mann-Whitney test for post-treatment and post-control. Results: The results of the Wilcoxon statistical test pre-post-treatment obtained = 0.000 and pre-post-control obtained = 0.093. The results of post-treatment and control group obtained = 0.009 and value = 0.05. It means that there is an effect of discharge planning on the stability of blood sugar levels in type 2 DM patients at A. Yani Islamic Hospital, Surabaya. Conclusion: The conclusion of this study is discharge planning can affect the stability of blood sugar levels in patients with diabetes mellitus type 2.
Protein tubuh berfungsi besar dalam proses metabolisme dan akan dimanfaatkan tubuh terutama jaringan dalam dalam proses aktifitas tubuh, namun seiring berjalannya waktu dan usia tubuh akan mengalami perubahan aktifitas. Semakin bertambah usia semakin banyak jaringan juga akan mengalami inaktif. Penelitian ini bertujuan untuk mengetahui ada tidaknya perbedaan protein urine ibu muda dengan lansia di desa kedungpandan, Kec. Jabon, Sidoarjo. Desain penelitian digunakan observasi analitik dengan pendekatan cross sectional. Populasi penelitian adalah 38 dan ditentukan berdasar rumus slovin ditentukan 33 sampel yaitu 33 sampel lansia dan 33 sampel ibu muda. Teknik pengambilan sampling dilakukan menggunakan teknik probability sampling. Hasil penelitian yang dilakukan berdasarkan uji Mann-Whitney menunjukkan bahwa p> 0,05 yaitu 0,379 menunjukkan bahwa tidak ada perbedaan antara protein urine pada Ibu muda dengan protein urine pada lansia di desa Kedungpandan, Kec Jabon, Sidoarjo
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