Corona Virus Diseases 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome corona virus 2 (SAR-CoV-2) which causes respiratory infections. This disease requires a large cost in the management process. Therefore, this research aims to analyze the cost-effectiveness in the use of azithromycin and levofloxacin antibiotics in the treatment of COVID-19 at a General hospital in Makassar City. This is an observational cross-sectional research with a prospective data collection method (January-March 2021) and a total sampling technique. Furthermore, data were taken from medical records and part of the financial information system, including patients' characteristics data (medical record number, patient initials, age, gender), clinical data (diagnosis, swab-test results), drug use data (dosage, rules of use, and duration of drug administration), and total medical costs (healthcare perspective: drug, treatment, laboratory, and radiology costs). Moreover, the effectiveness of this study was measured by the number of patients that were declared cured (negative swab-test). The results showed that the ACER value of the levofloxacin and azithromycin antibiotic were Rp. 191,705 and Rp. 157,359 respectively. These results indicate that the azithromycin antibiotic therapy group is more cost-effective compared to the levofloxacin group.
Measuring the quality of life can be used as a reference for the success of an action or therapy as well as initial data in formulating the right action for the patient. This study aims to provide an overview of the quality of life of patients with chronic renal failure who seek treatment at the Hasanuddin University teaching hospital. The research design used was an observational cross-sectional design with data collection carried out by filling out a questionnaire prospectively. The subjects of the study were chronic renal failure patients undergoing hemodialysis who met the inclusion and exclusion criteria and were selected using a non-random sampling technique by means of total sampling. The patient's quality of life was measured using the Kidney Disease Quality of Life Short Form (KDQOL-SFtm) Indonesian version 1.3 questionnaire. A total of 30 patients were willing to participate in this study. The results of the study on 30 patients with chronic renal failure, there were 7 out of 19 scale/item having a not good, namely burden of kidney disease, work status, sleep, physical functioning, role-physical, pain, and general health. The average value of 19 scale/item shows an average score of> 59.37, which is 63.86 which belongs to the good quality of life category.
Jumpai (Glinus Oppoitifolius (L.) Aug. DC) contains flavonoids compounds that can act as antioxidants by donating hydrogen so as to stabilize the lack of electrons in free radicals. This study aims to determine the antioxidant potential of stem, leaf, and flower extracts by looking at the IC50 value. The stems, leaves, and flowers were extracted by maceration using 70% l ethanol solvent. The results of the antioxidant activity test using the DPPH method (2,2-diphenyl-1-picrilhydrazil) showed very strong antioxidant activity with IC50 values of 9.523 µg / ml stem, 32.89 µg / ml leaves, and 23.07 µg / ml flowers with vitamin comparisons. C obtained IC50 value of 1,698 µg / ml. Based on these results, it can be rejected that the stems, leaves, and flowers have antioxidant activity with a very strong category against DPPH free radicals (2,2-diphenyl-1-picrilhydrazil).
Infeksi saluran kemih (ISK) bawah seperti uretritis, sistisis, epididimis, prostatitis merupakan inflamasi kandung kemih yang paling sering disebabkan oleh infeksi asenden dari uretra. Tujuan penelitian ini yaitu untuk mengetahui pengobatan apa saja yang diberikan pada pasien ISK dan mengetahui kerasionalan penggunaan antibiotik pada pasien ISK. Penelitian ini dilakukan di Rumah Sakit Pendidikan Universitas Hasanuddin (RSP UNHAS) pada tahun 2021 - 2022. Sampel yang digunakan dalam penelitian ini adalah rekam medik pasien ISK rawat jalan. Penilaian kondisi pasien dilakukan dengan membandingkan data pada literatur Drug Information Handbook edisi 24, Guideline Urological Infections 2015 dan modul penggunaan obat rasional Kemenkes RI 2011. Hasil penelitian menunjukkan bahwa pada pasien ISK bawah paling banyak menderita pada pasien perempuan (57,3%) dibandingkan dengan laki-laki (41,3%). Berdasarkan usia ISK bawah tertinggi terjadi pada kelompok umur 23-78 dibandingkan dengan usia <22 tahun. Penggunaan antibiotik rasional sebanyak 70 kasus (92,01%) dan melebihi waktu yang direkomendasikan sebanyak 4 kasus (5,3%). Akan tetapi sebagian besar kasus tidak rasional disebabkan oleh kondisi penyakit pasien yang tidak membaik.
Motivasi belajar memiliki peran yang penting dalam proses penerimaan pelajaran yang dilakukan di sekolah. Anak-anak sudah terlalu nyaman dengan sekolah online dan tidak tatap muka sehingga pembelajaran tidak intens seperti sedang di sekolah. Pelaksanaan kegiatan dilakukan dengan metode ceramah, tutorial, serta diskusi dan tanya jawab. Kegiatan ini terlaksana dengan baik dan lancar. Seluruh peserta dapat mengikuti dengan baik dan sangat aktif berperan serta selama kegiatan berlangsung. Anak-anak di lingkungan Boontopajja dan di lingkungan Jamarang bersemangat dalam mengikuti kegiatan ini dengan bermain sambil belajar. Melalui kegiatan ini dapat memberikan motivasi belajar sehingga dapat menghasilkan pengaruh yang positif dan signifikan terhadap hasil belajar siswa. Berdasarkan hal tersebut, kegiatan pengembalian semangat belajar yang dilakukan telah sesuai. Melalui kegiatan ini diharapkan mampu menggugah semangat belajar siswa.
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