have higher daytime systolic BP (137±10 vs 125±10 mmHg; p<0.001) and rates of atrial fibrillation (13.2% vs 4.9% ; p= 0.031) compared to those with normal nocturnal BP, which could have confounded the analysis. There was a significant difference in median NT-proBNP across all dipping groups (p=0.043). Risers had the highest plasma NT-proBNP in comparison to other dipping groups combined:198pg/mL (IQR: 119-198) vs 135 pg/mL (IQR: 82.25-234.75) (p=0.02). (See figure 1). Conclusion Patients with NH had higher plasma NT-proBNP levels than those without nocturnal hypertension. Risers had the highest NT-proBNP data and therefore may be at increased risk of heart failure compared to other subgroups. This study provides evidence that nocturnal hypertension and abnormal dipping, pattern is associated with adverse cardiac physiological changes. This observation lends support for initiating the use of 24hour-ABPM to identify those with subclinical target organ damage for risk stratification and individualized treatment strategies.
Introduction Readmission following a percutaneous coronary intervention (PCI) procedure is undesirable, being associated with patient morbidity and financial penalties. US data suggest 30 day readmission rates of approximately 10%, however little data is available within the UK. Reductions in the length of stay following PCI potentially increase the likelihood of early readmission. This study reviewed readmission's following PCI undertaken in a non-surgical PCI centre in the UK. Methods Hospital admission databases were reviewed for all patients who had undergone a PCI at the centre. All patients who were readmitted to the Trust within 30 days of their PCI were identified, and a retrospective analysis was then undertaken of their hospital records. Results The data set comprised of 3754 patients who had all undergone at least one PCI procedure over the past 6 years. Of these, 409 patients (10.9%) were readmitted within 30 days. A significantly greater proportion of readmission's within 30 days had an index PCI for acute coronary syndrome (ACS, 63.8% vs. 49.6%, p<0.01). Index PCI procedural success was high and comparable between the group of patients who were readmitted and those who were not.
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