45 Evaluating the impact of COVID-19 on regional primary percutaneous coronary intervention service during the first wave of COVID-19

Abstract

have higher daytime systolic BP (137±10 vs 125±10 mmHg; p<0.001) and rates of atrial fibrillation (13.2% vs 4.9% ; p= 0.031) compared to those with normal nocturnal BP, which could have confounded the analysis. There was a significant difference in median NT-proBNP across all dipping groups (p=0.043). Risers had the highest plasma NT-proBNP in comparison to other dipping groups combined:198pg/mL (IQR: 119-198) vs 135 pg/mL (IQR: 82.25-234.75) (p=0.02). (See figure 1). Conclusion Patients with NH had higher plasma NT-proBNP levels than those without nocturnal hypertension. Risers had the highest NT-proBNP data and therefore may be at increased risk of heart failure compared to other subgroups. This study provides evidence that nocturnal hypertension and abnormal dipping, pattern is associated with adverse cardiac physiological changes. This observation lends support for initiating the use of 24hour-ABPM to identify those with subclinical target organ damage for risk stratification and individualized treatment strategies.

Evaluating the Impact of COVID-19 on a Regional Primary Percutaneous Coronary Intervention Service During the First Wave of COVID-19

“…COVID-19 significantly reduced the number of pPCIs performed during the first wave of the epidemic at the Belfast trust and this is in agreement with 23 Reproduced with permission from BMJ Publishing Group and British Cardiovascular Society. findings in other studies; nevertheless, no referrals were inappropriately turned down because of COVID-19 at our regional centre.…”

“…CABG = coronary artery bypass graft; pPCI = primary percutaneous coronary intervention. Source: Olusan et al 2021 23. Reproduced with permission from BMJ Publishing Group and British Cardiovascular Society.…”