Objectives: To evaluate quality standards and to screen antioxidant activity of Cuvacakutori Chooranam (CC) a poly herbomineral Siddha formulation. Methods: The drug was prepared with authenticated ingredients. Powder microscopic, phytochemical, physicochemical, HPTLC fingerprint profiling (n-hexane, successive chloroform, successive ethanol), total phenol and flavonoid estimation, 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging and superoxide scavenging activities of CC were studied. Results: Microscopic studies revealed diagnostic features to identify the formulation using microscope. Preliminary phytochemical screening revealed the presence of different secondary metabolites, unique chromatographic fingerprint and antioxidant activities. Conclusion: The powder microscopic characters and the evolved physicochemical data arrived could serve as a reference tool for quality control. The presence of different categories of phytochemicals and antioxidant activity of the drug gives broad scope for further efficacy studies of this drug.
Preparation of NKC Vitex negundo and Piper betle were collected from the nearby places. Allium sativum and Piper nigrum were procured from the market. All the plants were authenticated with reference to floras. The fresh leaves of Vitex negundo and Piper betle were shade dried, along with Piper nigrum and Allium sativum (fresh), powdered coarsely (NKC) and stored in an air tight container (Table 1).
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