Concordance of OCT and brush cytology with the final diagnosis in patients with nonneoplastic strictures was 100% for both techniques; in the presence of a neoplastic MPD stricture, values were 100% and 66.7%, respectively.In conclusion this pilot study showed that OCT is feasible during ERCP, could distinguish a non-neoplastic from a neoplastic MPD wall with a diagnostic accuracy superior to brush cytology, but appeared to be unable to discriminate between a normal structure and chronic pancreatitis ductal changes.
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