Metastases to the thyroid gland—a report of six cases

Ultrasonographic Classification of the Metastases to the Thyroid Gland

“…Conversely, many clinical studies have showed that the most frequent primary non-thyroidal malignancy resulting in symptomatic or clinically evident thyroid metastases was RCC. 3,13,14) In the present study, the lung was the most frequent origin of thyroid metastases, corresponded with autopsy studies. We supposed that the subclinical manifestation of thyroid metastases was detected more frequently than the past, because the clinical application of CT and 18 FDG PET-CT has gradually been increasing in the patients with malignancies.…”

Malignant melanoma with synchronous thyroid metastases: case report and literature review

“…Thyrotoxicosis, as observed in our patient, may be caused by invasion and damage to thyroid follicles by rapid growing metastases, with release of hormone into the bloodstream, or by the production of thyroid hormones by the tumor cells (13,22). Unfortunately, the study of the etiology of the thyrotoxicosis in our patient's case was incomplete.…”

Hepatocellular carcinoma eats medullary thyroid carcinoma, a case of tumor-in-tumor metastasis

“…Although most patients reported to have thyroid metastases had advanced primary carcinomas, in some patients [27], including ours, the thyroid gland was the only site of metastasis. US guided FNAB is optimal in the diagnosis of thyroid tumors [28], with many reports of thyroid metastases also based on FNAB results [13,14,[17][18][19][20][21][22]. FNAB of the thyroid in our patient suggested a poorly differentiated carcinoma favoring metastasis but not expressing thyroglobulin, leading us to perform thyroid surgery.…”

“…The incidence of thyroid metastases in clinical reports seems to have increased recently [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22], with the most common primary carcinoma site being the kidney, followed by breast and lung [8][9][10][11][12][13][14].…”

“…Clinical reports have suggested, however, that the incidence of these metastases is increasing. The most common primary carcinoma sites in clinical reports are the kidneys, breasts, and lungs [8][9][10][11][12][13][14], although other primary carcinomas can also metastasize to the thyroid gland [15][16][17][18][19][20][21][22][23][24][25][26][27].Hepatocellular carcinoma (HCC) rarely metastasizes to the thyroid [6,23,[25][26][27]. Here, we describe a patient with an HCC metastasis to within a medullary thyroid carcinoma (MTC), that is, a tumor-in-tumor metastasis.…”