is a chronic autoimmune disease characterized by changes in the growth and differentiation of the epidermis. 2-5 % of the population of the planet have psoriasis, and it is 30 % in the structure of skin diseases. The multifactorial concept of the pathological process in psoriasis determines a wide range of pharmacotherapy of this disease. Modern antipsoriatic agents are not effective enough and have a variety of side effects.Aim. To summarize the existing scientific literature data conserning the possibility of treating psoriasis with carboxytherapy.Results and discussion. Carboxytherapy is an important part of the treatment and rehabilitation of patients with psoriasis. The antipsoriatic effect of carboxytherapy is realized through the local and resorptive effect of CO 2 : antiproliferative, antiinflammatory, antioxidant, antimicrobial, antihypertrophic, reparative and analgesic. Carboxytherapy in psoriasis promotes tissue detoxification, improves immunity, improves tissue trophism, and eliminates venous-interstitial lymphatic stagnation due to hemodynamic, tissue, and biochemical mechanisms of action of СО 2 .Conclusions. Carboxytherapy as an additional alternative to pharmacotherapy has a synergistic effect together with formulary therapy, but at the same time reduces the dosage of approved drugs and their side effects.
The potential of carboxytherapy in diseases of the urogenital system organs Recently carboxytherapy has been widely used for the treatment of many diseases, and it is associated with the high efficiency and low cost. Carboxytherapy as the method of treatment has been used for 70 years in the international medical practice and more than 50 years in aesthetic medicine. Aim. To substantiate the use of carboxytherapy as an innovative method of treatment for diseases of the urogenital system organs. Materials and methods. The analysis of scientific sources concerning the treatment of sexual dysfunction, erosion of the cervix, menopause, vulvovaginal atrophy, initial stages of the stress urinary incontinence, erectile dysfunction, and impotence was performed. Results. It has been determined that various variants of carboxytherapy can be used to obtain the antihypoxic, reparative-regenerative, spasmolitic, anti-inflammatory, analgesic and antioxidant effects in clinical practice as a result of the treatment. Patients with different pathologies of the urogenital system noted improvement in functioning of urogenital organs, release of pain, decrease in inflammation, mood stability, and good mental and physical performance. Therefore, the quality of life has been improved. Conclusions. Thus, СО 2 can be considered as a unique medicinal product, and carboxytherapy as an alternative treatment for many diseases.
The aim of the study was to analyze the mechanisms of action and pharmacodynamics of carboxytherapy in diseases of the cardiovascular system (CVS). Materials and methods. An analysis of domestic and foreign experience in the use of carboxytherapy for diseases of CVS. Results and discussions. The mechanism of action of carboxytherapy is based on the principle of the introduction of carbon dioxide (CO2) in the patient's body, due to which many pathological disorders can be eliminated. Inhalation and non-inhalation introduction of CO2 into the body has been used for medicinal purposes for many decades. The empirical (off label) use of this therapy in course of time has gained a wide clinical evidence base. There is a large amount of clinical evidence in the world of the effective use of carboxytherapy in many fields of medicine, including those with CVS diseases. It is proved that CO2 introduced into the body penetrates freely through cell membranes and has antihypoxic, vasodilating, antioxidant, anti-ischemic, antispasmodic and other positive effects. Therefore, carboxytherapy contributes to a complex of pharmacological effects inherent of traditional antianginal, hypotensive, antispasmodic and other drugs that are widely used in the treatment of CVS diseases. Conclusions. An analysis of domestic and foreign experience in carboxytherapy shows that the effects of CO2 in diseases of the CVS are achieved by improving oxygenation and microcirculation, anti-anginal, anti-inflammatory, antihypertensive, antispasmodic, anti-oxidant, and analgesic effects of this gas. Carboxytherapy is an alternative, promising and safe method of treating diseases of the cardiovascular system.
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Diseases of the musculoskeletal system are quite common diseases. Moreover, the use of pharmacotherapy may not always be effective, which is associated with a large number of side effects of modern non-steroidal anti-inflammatory drugs (NSAIDs). The way out of the situation can be the use of carboxytherapy (CO2 therapy), which has a complex of pharmacological effects: analgesic, anti-inflammatory, antispasmodic, antihypoxic and antioxidant.These CO2 effects are used to eliminate the symptom complex associated with pain, inflammation, ischemia, hypoxia, and joint stiffness. The use of carboxytherapy in orthopedics is primarily aimed at eliminating pain in various diseases of the spine, joints, muscles in the back, neck, thighs, knees and other organs. The main target of the action of carboxytherapy in diseases of the musculoskeletal system are Zakharyin – Geda zones, trigger points, myofibralgia zones and acupuncture points.When CO2 affects these zones and points, vasodilation, muscle relaxation and increased tissue oxygenation reflexively occur, which leads to a decrease in inflammation, pain and other functional disorders in the joints and muscles. Due to the polypathopathogenetic pharmacodynamics of CO2, carboxytherapy is often used for post-traumatic and inflammatory conditions of joints, arthrosis, and other acute and chronic joint pathologies of various etiologies.In addition, with combined pharmacotherapy of these diseases, carboxytherapy reduces the duration of NSAIDs and other drugs, reduces their dosage, which reduces the risk of side effects and increases the effectiveness of CO2 therapy.
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