Zwitterionic functionalised mesoporous silica nanoparticles for alendronate release

Highly sensitive aptasensor for the detection of SARS-CoV-2-RBD using aptamer-gated methylene blue@mesoporous silica film/laser engraved graphene electrode

“…3 B shows the FT-ATR spectrum of the aptamer gated-MB@MPSF/LEGE. As it can be seen, an absorption band at about 3400 cm −1 due to the –NH 2 stretching, 2930 cm −1 and 2900 due to the –CH x stretching, an absorption band at 2300 cm −1 due to the –N-H asymmetric stretching, an absorption band at 1580 due to the –N-H bending, absorption bands at 1150 cm −1 and 926 cm −1 due to the –Si-O-Si bending, the –Si-OH, respectively ( Nechikkattu et al, 2019 ), an absorption band at 1538 cm −1 due to the –C O stretching, an absorption band at 1376 cm −1 due to the –C-N stretching of amide III, an absorption band at 1277 cm −1 due to the –PO 2 − stretching in the aptamer probe, an absorption band at 792 cm −1 due to the = C–H bending, an absorption band at 734 cm −1 due to the -C-S-C bending (in the aromatic structure of MB) are clearly seen ( Nowak et al, 2019 ).…”

pH-Sensitive Polyacrylic Acid-Gated Mesoporous Silica Nanocarrier Incorporated with Calcium Ions for Controlled Drug Release

“…The existence of calcium ions by the incorporation with carboxylate functional groups can be measured by the method of EDS mapping, which will be mentioned later. The structure without loss of well-arranged mesopore arrays in a long range after modification steps is preferred for loading guest molecules ( Figure 2 c,d) [ 72 ].…”

Biofunctionalization of titanium surfaces with alendronate and albumin modulates osteoblast performance

“…Finally, the N 1s spectrum ( Figure 4 d) confirms the functionalization due to the NH 3 + [ 42 ] peak at 401.2 eV and the organic binding C–N at 399.2 eV [ 40 ]. The presence of NH 3 + suggests that it could have been generated by the formation of a zwitterionic amine structure, which favors adsorption through the C-PO(OH) 2 group [ 43 , 44 ]. Figure 4 e shows the high-resolution spectrum for P 2p, which contains two contributions, P 2p 1 / 2 (134.5 eV) and P 2p 3 / 2 (133.3 eV) [ 36 ], confirming the presence of alendronate on the TiO 2 surface.…”