WITHDRAWN: Optimization of trans-resveratrol extraction from peanut kernels using supercritical fluid extraction

Jitrangsri, Kritamorn; Chaidedgumjorn, Amornrut; Satiraphan, Malaï

doi:10.1016/j.ajps.2015.11.002

Cited by 4 publications

(3 citation statements)

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“…Resveratrol content was quantified at optimized conditions, and it was analyzed by Agilent 1200s HPLC system, United States. The analytical conditions were validated and described in our previous work 14 . Resveratrol content was calculated from external standard calibration curve in the range of 2.0–10.0 μg/ml and reported as μg/g dry peanut sample.…”

Section: Methodsmentioning

confidence: 99%

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An antioxidative potential‐based comparison of different peanut extraction methods, optimized through response surface methodology

Jitrangsri,

Chaidedgumjorn,

Satiraphan

2023

Journal of Chemometrics

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In this research, response surface methodology was employed in order to find the most efficient conditions to produce peanut extracts with the highest antioxidative potential (by DPPH, ABTS, FRAP, and ORAC tests) from ultrasound‐assisted (UAE) and microwave‐assisted (MAE) extractions. The optimal conditions for UAE were 75 ml of 30%v/v ethanol as extraction solvent, extraction temperature of 65°C, and 180 min extraction time. Optimal conditions for MAE were 15 ml of 30%v/v ethanol as extraction solvent, extraction temperature of 80°C, and 90 s extraction time. The generated models presented a reliable antioxidative response by showing non‐difference between experimental and predicted values within a 95% confidence level. Characteristics such as antioxidant activities, TPC, resveratrol, and TFC were used to compare the effectiveness of the obtained extracts and the SLE extract from our previous work. The UAE extract displayed higher extraction efficiency than that of MAE in terms of higher levels of all responses (p < 0.05). Slightly lower antioxidant values of MAE might be due to the limited solvent volume used, which was five times less than that of UAE. Moreover, the high efficacy of MAE was confirmed by its extraction time, which was 120 times shorter than that of UAE. Ultimately, the correlation analysis implied that the antioxidant activity of peanut extracts was contributed by TPC rather than resveratrol or TFC, and the revealed TPC in this study was higher than previous reports.

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Section: Methodsmentioning

confidence: 99%

“…The analytical conditions were validated and described in our previous work. 14 Resveratrol content was calculated from external standard calibration curve in the range of 2.0-10.0 μg/ml and reported as μg/g dry peanut sample.…”

Section: Resveratrol Contentmentioning

confidence: 99%

An antioxidative potential‐based comparison of different peanut extraction methods, optimized through response surface methodology

Jitrangsri,

Chaidedgumjorn,

Satiraphan

2023

Journal of Chemometrics

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“…Supercritical fluid extraction (SFE) is a safe, non‐toxic, and pollution‐free extraction method. The purity of resveratrol extracted by this method is quite high, but the extraction rate is very low, requiring multiple extractions (Jitrangsri et al, 2015). The enzymatic hydrolysis method uses cellulase to break the glycosidic bond of resveratrol in the glycosidic form and convert it into a free state of resveratrol monomer, so as to improve the extraction rate of resveratrol (Wang et al, 2016).…”

Section: Bioactive Factor—resveratrolmentioning

confidence: 99%

Review on chemical compositions and biological activities of peanut ( Arachis hypogeae L.)

Guo

et al. 2022

Journal of Food Biochemistry

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Peanut (Arachis hypogeae L.), as an annual leguminous crop, is also known as earthnut, monkey nut, and goobers. It is a major oilbearing crop and is widely cultivated throughout the world, of which China and India have the largest cultivation area and production (Arya et al., 2016). Peanuts ranks as the 13th largest food crop and the 4th largest oil crop in the world (Zhao et al., 2021). Unlike most plants, fruits of peanuts grow in soil, not on the ground. A complete peanut consists of peanut shells, peanut skins, and peanut seeds, in which peanut skins and peanut seeds are edible parts. Peanut seeds are rich in nutrients, oil content of about 50%, protein content of more than 20%, and mineral and vitamin contents are also rich (Yaw et al., 2008). Owing to its high oil content, peanut was once considered an unhealthy food. Peanut skins contain rich natural antioxidants such as polyphenol compounds, but it is usually considered a low-value by-product in food industries (Ballard et al., 2009;Dudek et al., 2017). It is valuable to study the biological activity of peanut skins so that they are not wasted as by-products. Peanut has multiple uses and is used to make edible oil, emulsifier, animal

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Resveratrol and Alzheimer’s Disease: Mechanistic Insights

et al. 2016

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Alzheimer's disease (AD) is the leading cause of dementia in the elderly and is characterized by progressive cognitive and memory deficits. The pathological hallmarks of AD include extracellular senile plaques and intracellular neurofibrillary tangles. Although several mechanisms have been used to explain the underlying pathogenesis of AD, current treatment regimens remain inadequate. The neuroprotective effects of the polyphenolic stilbene resveratrol (3,5,4'-trihydroxy-trans-stilbene) have been investigated in several in vitro and in vivo models of AD. The current review discusses the multiple potential mechanisms of action of resveratrol on the pathobiology of AD. Moreover, due to the limited pharmacokinetic parameters of resveratrol, multiple strategies aimed at increasing the bioavailability of resveratrol have also been addressed.

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WITHDRAWN: Optimization of trans-resveratrol extraction from peanut kernels using supercritical fluid extraction

Cited by 4 publications

References 1 publication

An antioxidative potential‐based comparison of different peanut extraction methods, optimized through response surface methodology

An antioxidative potential‐based comparison of different peanut extraction methods, optimized through response surface methodology

Review on chemical compositions and biological activities of peanut ( Arachis hypogeae L.)

Resveratrol and Alzheimer’s Disease: Mechanistic Insights

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