Weakly swirling flow in a model of blood vessel with stenosis: Numerical and experimental study

Gataulin, Y A; Zaitsev, D. K.; Смирнов, Е. М.; Fedorova, Ekaterina; Yukhnev, A D

doi:10.1016/j.spjpm.2016.02.005

Cited by 8 publications

(5 citation statements)

References 9 publications

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“…This growth creates significant problems in the circulatory system as it occludes or reduces the blood flow. Stenosis, if happening in the brain arteries, can cause cerebral concussions; or it results in myocardial infraction if it occurs in coronary arteries, which can lead to heart failure (Nadeem and Ijaz, 2015; Gataulin et al , 2015; Ellahi et al , 2014a, 2014b, 2015).…”

Section: Introductionmentioning

confidence: 99%

Simulation of cavitation of spherically shaped hydrogen bubbles through a tube nozzle with stenosis

Ellahi

Zeeshan

Hussain

et al. 2020

HFF

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Purpose The purpose of this study is to investigate the monodisperse cavitation of bubbly mixture flow for water and hydrogen mixture flows through a nozzle having a stenosis on the wall. Design/methodology/approach Two flow regions, namely, quasi-statically stable and quasi-statically unstable increase in the bubble radius, are considered. Different oscillating periods of bubbles in downstream corresponding to various values of Reynolds number are taken into account. The Range–Kutta method is used to tackle nonlinear coupled system of governing equations. Findings It is observed that for the larger values of Reynolds number, the void fraction at the upstream section, even at small values, yields instabilities at the downstream. Consequently, owing to sudden increase in the velocity, the bubbles strike the wall with high speed that eventually remove the existing stenosis. This process can be considered as an effective cardiac surgery for arteries with semi-blockage. Originality/value Original research work and to the best of author’s knowledge, this model is reported for the first time.

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Section: Introductionmentioning

confidence: 99%

Simulation of cavitation of spherically shaped hydrogen bubbles through a tube nozzle with stenosis

Ellahi

Zeeshan

Hussain

et al. 2020

HFF

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“…The helical blood flow may have an effect on the inner surface of the wall by washing and protecting the ascending thoracic aorta from atherosclerotic plaque formation . Even though a large amount of evidence indicates the role of swirling blood flow in the development of cardiovascular diseases, atherosclerosis being the most commonly occurring among them, it is yet unclear how these hemodynamics alteration affect wall remodeling in ATAAs . There are some studies which indicate that patient with aortic stenosis frequently develop helical blood flow patterns compared to healthy subjects .…”

Section: Discussionmentioning

confidence: 99%

“…65 Even though a large amount of evidence indicates the role of swirling blood flow in the development of cardiovascular diseases, atherosclerosis being the most commonly occurring among them, it is yet unclear how these hemodynamics alteration affect wall remodeling in ATAAs. 66 There are some studies which indicate that patient with aortic stenosis frequently develop helical blood flow patterns compared to healthy subjects. 67 Hence there is a pressing need to understand the impact of helical blood flow patterns on the aortic wall for potential interventions.…”

Section: Discussionmentioning

confidence: 99%

Computational prediction of hemodynamical and biomechanical alterations induced by aneurysm dilatation in patient‐specific ascending thoracic aortas

Jayendiran

Condemi

Campisi

et al. 2020

Numer Methods Biomed Eng

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The aim of the present work is to propose a robust computational framework combining computational fluid dynamics (CFD) and 4D flow MRI to predict the progressive changes in hemodynamics and wall rupture index (RPI) induced by aortic morphological evolutions in patients harboring ascending thoracic aortic aneurysms (ATAAs). An analytical equation has been proposed to predict the aneurysm progression based on age, sex, and body surface area. Parameters such as helicity, wall shear stress (WSS), time‐averaged WSS, oscillatory shear index, relative residence time, and viscosity were evaluated for two patients at different stages of aneurysm growth, and compared with age‐sex‐matched healthy subjects. The study shows that evolution of hemodynamics and RPI, despite being very slow in ATAAs, is strongly affected by morphological alterations and, in turn could impact biomechanical factors and aortic mechanobiology. An aspect of the current work is that the patient‐specific 4D MRI data sets were obtained with a follow‐up of 1 year and the measured time‐averaged velocity maps and flow eccentricity were compared with the CFD simulation for validation. The computational framework presented here is capable of capturing the blood flow patterns and the hemodynamic descriptors during the various stages of aneurysm growth. Further investigations will be conducted in order to verify these results on a larger cohort of patients and with long follow‐up times to finally elucidate the link between deranged hemodynamics, AA geometry, and wall mechanical properties in ATAAs.

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“…It was observed that the % volume of absolute LNH ≥ 0.6 had a significant correlation with flow eccentricity and maximal ATAA diameter. Eventhough there are many studies indicating the role of helicity in the development of cardiovascular diseases (Kilner et al, 1993;Caro et al, 1996;Stonebridge et al, 1996;Morbiducci et al, 2007;Liu et al, 2009Liu et al, , 2014, it is yet unclear how these hemodynamics alterations affect wall remodeling in ATAAs (Gataulin et al, 2015;Ha et al, 2016).…”

Section: Correlation Between Maximum Ataa Diameter and Hemodynamics D...mentioning

confidence: 99%

Hemodynamics alteration in patient-specific dilated ascending thoracic aortas with tricuspid and bicuspid aortic valves

Jayendiran

Campisi

Viallon

et al. 2020

Journal of Biomechanics

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Weakly swirling flow in a model of blood vessel with stenosis: Numerical and experimental study

Cited by 8 publications

References 9 publications

Simulation of cavitation of spherically shaped hydrogen bubbles through a tube nozzle with stenosis

Simulation of cavitation of spherically shaped hydrogen bubbles through a tube nozzle with stenosis

Computational prediction of hemodynamical and biomechanical alterations induced by aneurysm dilatation in patient‐specific ascending thoracic aortas

Hemodynamics alteration in patient-specific dilated ascending thoracic aortas with tricuspid and bicuspid aortic valves

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