Vitamina D3 e seus metabólitos para frangos de corte

Souza, Christiane Silva; Vieites, Flávio Medeiros

doi:10.21071/az.v63i241.588

Cited by 10 publications

(8 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In the other hand, reduced glutathione (GSH), oxidized glutathione (GSSH) and glutamine plasma levels were lower in the VD sufficient group [48] and no association was observed between VD and oxidative DNA damage [49]. Thus, the association between VD status and oxidative stress markers remains contradictory [50]. Taken together, these data suggest that VD deficiency may intensify cellular oxidative stress, while satisfactory levels of VD, may contribute reducing the oxidative stress.…”

Section: Discussionmentioning

confidence: 98%

The relationship between vitamin D deficiency and oxidative stress can be independent of age and gender

Câmara

Brandão

2021

International Journal for Vitamin and Nutrition Research

View full text Add to dashboard Cite

Abstract. The active vitamin D (1,25(OH)2D) acts through a nuclear receptor to perform several functions in cellular metabolism. 1,25(OH)2D participates directly in calcium homeostasis, regulates the immune system, nervous system, blood pressure, insulin secretion, among others. Vitamin D deficiency could also be associated with several diseases and increased cellular oxidative damage. The present study aimed to investigate whether lipid peroxidation and/or protein oxidation are affected by vitamin D deficiency and whether sunlight exposure/diet, gender, and age might influence this relationship. Vitamin D concentrations were obtained from the Heart Hospital database and a questionnaire was applied among the 212 participants. We used the inactive vitamin D (25(OH)2) in the analyses since 1,25(OH)2D has a short half-life and a low blood concentration. Lipid peroxidation and protein oxidation analyses were performed using spectrophotometry. Multivariate analyses suggested the participation of vitamin D deficiency (<30 ng/mL) and sunlight/diet in oxidative stress (p <0.05; R2 MDA: 0.562; R2 CG: 0.429). Multiple linear regression test show that the age and gender of patients are not interfering in the analyses (p>0.05). Therefore, we suggest that the relationship between vitamin D deficiency and oxidative stress can be independent of age and gender.

show abstract

Section: Discussionmentioning

confidence: 98%

The relationship between vitamin D deficiency and oxidative stress can be independent of age and gender

Câmara

Brandão

2021

International Journal for Vitamin and Nutrition Research

View full text Add to dashboard Cite

show abstract

“…As vitamin D 2 (ergocalciferol) potency is about 10 times lower than vitamin D 3 (cholecalciferol) for poultry, the last one is often used. To reach its main metabolically active form, 1,25-dihydroxycholecalciferol (1,25(OH) 2 D 3 ), vitamin D 3 must be hydroxylated first in the liver into 25-hydroxycholecalciferol (25(OH)D 3 ), then in the kidneys (Souza and Vieites, 2014). 1,25(OH) 2 D 3 has an important role in calcium and phosphorus homeostasis, bone growth and remodeling, and in the immune system (Kochupillai, 2008;Muszkat et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Effects of 1,25-dihydroxycholecalciferol and reduced vitamin D3 level on broiler performance and bone quality

et al. 2018

View full text Add to dashboard Cite

This study was conducted to evaluate the effect of two levels of vitamin D 3 with or without 1,25dihydroxycholecalciferol (1,25(OH) 2 D 3) on live performance and bone quality of broiler chickens. For that, we used a completely randomized design in a 2 × 2 factorial arrangement, with eight replicates of 30 Cobb ® 500 male broiler chicks each (n = 960). The two levels of vitamin D 3 and the addition or not of 0.5 µg 1,25(OH) 2 D 3 /kg were considered as main factors. The vitamin D 3 levels were: 2500/2000 IU/kg and 1250/1000 IU/kg for the starter (1 to 21 days) and grower (22 to 40 days) phases, respectively, with the first representing the levels used in industry (100%) and the second, a reduction in 50% of those levels. The 1,25(OH) 2 D 3 source was Solanum glaucophyllum. On days 21 and 40, one broiler per replicate was killed and long bones were removed for analyses of mineral percentage, bone mineral density, biomechanical properties, and morphology. No significant differences were found related to vitamin D 3 levels and the addition or not of 1,25(OH) 2 D 3 for live performance, mineral percentage, strength, stiffness, and morphology. Toughness was lower when 1,25(OH) 2 D 3 was used at 21 days, but this effect was not observed at 40 days of age. Bone mineral density was greater when 100% of vitamin D 3 was used at 40 days of age. The reduction of up to 50% of vitamin D 3 levels is sufficient to ensure performance and bone development of broilers at 21 and 40 days of age. The inclusion of 0.5 µg 1,25(OH) 2 D 3 /kg in addition to diets with sufficient levels of vitamin D 3 shows no effect on the improvement of those parameters at the same ages.

show abstract

“…A vitamina D 3 ativa quando fornecida em níveis elevados às aves, pode promover o retardo no crescimento, o eriçamento de penas, a poliúria, a desidratação e a incoordenação de movimentos e a debilidade de patas (Souza & Vieites 2014). No período experimental, não foram observados quaisquer sintomas de toxidez nos frangos de corte fêmeas.…”

Section: Resultsunclassified

“…Os autores citados observaram maior zona mineralizada nos ossos. Souza and Vieites (2014) reportaram que o uso de vitamina D 3 e/ou seus metabólitos não tem prejudicado o desempenho zootécnico de frangos de corte. Ainda, tem demonstrado melhorias na utilização do fósforo e aumento no teor de cinza nos ossos.…”

Section: Tratamentosunclassified

“…A forma hormonal da vitamina D (1,25(OH) 2 D 3 ) foi identificada pela primeira vez no intestino de pintos raquíticos Leghorn branca (Norman 1987). A vitamina D 3 e seus metabólitos participam da regulação da homeostase de cálcio e do fosfato, por meio de mecanismo que aumenta a captação intestinal destes, diminuindo as perdas renais e estimulando a reabsorção óssea, quando necessário (Souza & Vieites 2014).…”

Section: Introductionunclassified

See 1 more Smart Citation

1,25-dihidroxicolecalciferol de origem herbal (Solanum glaucophyllum) mantém o desempenho e a qualidade óssea de frangos de corte fêmeas durante restrição de cálcio e fósforo

et al. 2018

View full text Add to dashboard Cite

1,25-dihydroxycholecalciferol from plant source (Solanum glaucophyllum) maintains the performance and bone quality of female broilers during restriction of calcium and phosphorus sUMMarY The supplementation with 1,25-dihydroxycholecalciferol (1,25(OH) 2 D 3 ) has been evaluated as an alternative to reduce dietary concentrations of calcium (Ca) and phosphorus (P). Thus, the objective of this study was to determine the best level of dietary supplementation of 1,25(OH) 2 D 3 from plant source (Solanum glaucophyllum) to female broiler chickens restricted in Ca and available P (aP). A total of 684 day-old chicks were weighted and equally distributed in a completely randomized design with six treatments and six replications of 19 birds. Treatments consisted of a positive control (PC): corn-and soybean-meal diet formulated to reach animals' nutritional requirements; a negative control (NC): PC diet with 15% reduction in dietary Ca and aP concentrations; and four NC diets supplemented with 0.5, 1.0, 1.5 or 2.0 µg/kg of 1,25(OH) 2 D 3 . Growth performance was evaluated at 42 days; bone mineralization characteristics, at 21 and 33 days. Broilers fed NC decreased feed intake (P<0.05), but not weight gain and feed conversion ratio. At day 21, the supplementation of NC with 1,25(OH 2 )D 3 did not return tibiotarsus ash to the same level as that observed in broilers fed PC, but it kept other bone characteristics at simmilar values. At day 33, broilers fed NC supplemented with 1,25(OH 2 )D 3 showed higher bone weight. Overall, broilers fed 2.0 µg/kg of 1,25(OH) 2 D 3 had higher ash content than those fed PC. additional keYwordsActive D3 vitamin. Ash. Bone strength.

show abstract

Vitamina D3 e seus metabólitos para frangos de corte

Cited by 10 publications

References 24 publications

The relationship between vitamin D deficiency and oxidative stress can be independent of age and gender

The relationship between vitamin D deficiency and oxidative stress can be independent of age and gender

Effects of 1,25-dihydroxycholecalciferol and reduced vitamin D3 level on broiler performance and bone quality

1,25-dihidroxicolecalciferol de origem herbal (Solanum glaucophyllum) mantém o desempenho e a qualidade óssea de frangos de corte fêmeas durante restrição de cálcio e fósforo

Contact Info

Product

Resources

About