Using Skin Models to Assess the Effects of a Pre-Work Cream

Mühlen, A. Zur; Klotz, A.; Allef, P.; Weimans, S.; Veeger, M.; Thörner, B.; Eichler, Jürgen

doi:10.1159/000099601

Cited by 6 publications

(3 citation statements)

References 30 publications

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“…BCs are used to prevent the irritant effect caused by occupational exposure and are recommended for application before and during work. Some authors call them prework creams [8,9,10]. They have also been called ‘invisible gloves' but the term ‘skin protective creams' is more appropriate [10].…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of Barrier Creams against Irritant Contact Dermatitis

Mostosi

Simonart

2016

Dermatology

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Introduction: Skin tissue is frequently exposed to various irritant substances in the workplace, particularly in wet work, which can lead to the development of occupational contact dermatitis. ‘Barrier' creams (BCs) are well known, and their applications are still the subject of many studies and controversies. Methods: We searched all controlled trials investigating BCs against cutaneous irritants in humans published between 1956 and December 2014 from MEDLINE, PubMed, reference lists and existing reviews. Results: Thirty-nine studies about the effects of BCs against skin irritants in humans were selected. Among these, 27 trials in healthy volunteers were found to show many differences with regard to BCs and irritants used, their quantities, test locations, procedures and assessment methods. Finally, 14 patch test trials assessed by clinical scoring and evaporimetry emerged. Although the findings were generally positive, only few findings could be cross-checked from all the data, and vehicles seem to be as effective as BCs. Conclusion: Although this review highlights the poor quality and the lack of standardization of most studies, BCs seem to have protective effects against irritants. Further well-designed, adequately powered randomized controlled trials with clinical and biophysical assessments are required.

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Section: Introductionmentioning

confidence: 99%

Effectiveness of Barrier Creams against Irritant Contact Dermatitis

Mostosi

Simonart

2016

Dermatology

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“…Although the relevance and great effectiveness of target orientated teaching campaigns is of no doubt [11], also regular use of hand creams can reduce the risk for dermatitis by almost 50% [9], [12]. Despite this encouraging result, the advantage of barrier creams compared to bland emollients for skin protection is not clearly demonstrated and only scant literature exists on this issue [12], [13], [14], [15], [16], [17]. …”

Section: Introductionmentioning

confidence: 99%

Practices of skin care among nurses in medical and surgical intensive care units: results of a self-administered questionnaire

Große-Schütte

Assadian²,

Hübner³

et al. 2011

GMS Krankenhaushygiene Interdisziplinär; 6(1):Doc08; ISSN 1863-5245

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“…Various in vivo and vitro methods were developed in recent times for evaluating SPC efficacy [ 10 - 16 ]. Each of the methods probably presents some advantages but also disadvantages.…”

Section: Introductionmentioning

confidence: 99%

Skin protection creams in medical settings: successful or evil?

Xhauflaire-Uhoda¹,

Macarenko²,

Denooz

et al. 2008

J Occup Med Toxicol

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Background: Chronic exposure to mild irritants including cleansing and antiseptic products used for hand hygiene generates insults to the skin. To avoid unpleasant reactions, skin protection creams are commonly employed, but some fail to afford protection against a variety of xenobiotics. In this study, two skin protection creams were assayed comparatively looking for a protective effect if any against a liquid soap and an alcohol-based gel designed for hand hygiene in medical settings.

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Using Skin Models to Assess the Effects of a Pre-Work Cream

Abstract: Skin models support the understanding of the interaction of irritants and pre-work creams. Because they are in vitro models, there are no limitations regarding the selection of irritants, which offers numerous opportunities to test a broad range of workplace irritants.

Cited by 6 publications

References 30 publications

Effectiveness of Barrier Creams against Irritant Contact Dermatitis

Effectiveness of Barrier Creams against Irritant Contact Dermatitis

Practices of skin care among nurses in medical and surgical intensive care units: results of a self-administered questionnaire

Skin protection creams in medical settings: successful or evil?

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