Skin protection creams in medical settings: successful or evil?

Xhauflaire-Uhoda, Emmanuelle; Macarenko, Elena; Denooz, Raphaël; Charlier, Corinne; Pierard, Gérald

doi:10.1186/1745-6673-3-15

Cited by 17 publications

(11 citation statements)

References 32 publications

(29 reference statements)

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“…Camphor is an odorous terpens used in many cleaning and medical products due to its anti-microbial and local anesthetic properties [40], [41]. Alpha-bisabolol is an ingredient of skin protection creams due to its anti-irritant, anti-inflammatory and anti-microbial properties [42]. There is no data available on the toxicity of butane, benzaldehyde, benzoic acid and α-bisabolol in humans…”

Section: Discussionmentioning

confidence: 99%

VOC Contamination in Hospital, from Stationary Sampling of a Large Panel of Compounds, in View of Healthcare Workers and Patients Exposure Assessment

et al. 2013

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BackgroundWe aimed to assess, for the first time, the nature of the indoor air contamination of hospitals.Methods and FindingsMore than 40 volatile organic compounds (VOCs) including aliphatic, aromatic and halogenated hydrocarbons, aldehydes, alcohols, ketones, ethers and terpenes were measured in a teaching hospital in France, from sampling in six sampling sites – reception hall, patient room, nursing care, post-anesthesia care unit, parasitology-mycology laboratory and flexible endoscope disinfection unit – in the morning and in the afternoon, during three consecutive days. Our results showed that the main compounds found in indoor air were alcohols (arithmetic means ± SD: 928±958 µg/m3 and 47.9±52.2 µg/m3 for ethanol and isopropanol, respectively), ethers (75.6±157 µg/m3 for ether) and ketones (22.6±20.6 µg/m3 for acetone). Concentrations levels of aromatic and halogenated hydrocarbons, ketones, aldehydes and limonene were widely variable between sampling sites, due to building age and type of products used according to health activities conducted in each site. A high temporal variability was observed in concentrations of alcohols, probably due to the intensive use of alcohol-based hand rubs in all sites. Qualitative analysis of air samples led to the identification of other compounds, including siloxanes (hexamethyldisiloxane, octamethyltrisiloxane, decamethylcyclopentasiloxane), anesthetic gases (sevoflurane, desflurane), aliphatic hydrocarbons (butane), esters (ethylacetate), terpenes (camphor, α-bisabolol), aldehydes (benzaldehyde) and organic acids (benzoic acid) depending on sites.ConclusionFor all compounds, concentrations measured were lower than concentrations known to be harmful in humans. However, results showed that indoor air of sampling locations contains a complex mixture of VOCs. Further multicenter studies are required to compare these results. A full understanding of the exposure of healthcare workers and patients to complex mixtures of chemical compounds can then be related to potential health outcomes.

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Section: Discussionmentioning

confidence: 99%

VOC Contamination in Hospital, from Stationary Sampling of a Large Panel of Compounds, in View of Healthcare Workers and Patients Exposure Assessment

et al. 2013

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“…A positive patch test in both areas but with a much higher intensity in the irradiated area, usually called a photo-augmented patch test reaction, can occur with contact allergens with some photoactive potential, e.g., etofenamate, ketoprofen, and UV fi lters [ 45 ], and represent the association of allergic and photoallergic contact dermatitis or a photo-augmentation of contact allergy [ 46 ].…”

Section: Photopatch Testing: Reading and Interpretation Of Resultsmentioning

confidence: 99%

Quick Guide to Contact Dermatitis

Johansen¹,

Lepoittevin²,

Thyssen³

2016

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“…One main indication is found in the field of skin irritation while avoiding the risk of in vivo hazards. Skin barrier formulations are conveniently tested using CXM 50. Another indication deals with comparative assessments of penetration enhancers commonly used in some topical formulations 51…”

Section: Analytical Morphology Of Skin Strippingsmentioning

confidence: 99%

From observational to analytical morphology of the stratum corneum: progress avoiding hazardous animal and human testings

Pierard¹,

Courtois²,

Ritacco³

et al. 2015

CCID

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BackgroundIn cosmetic science, noninvasive sampling of the upper part of the stratum corneum is conveniently performed using strippings with adhesive-coated discs (SACD) and cyanoacrylate skin surface strippings (CSSSs).MethodsUnder controlled conditions, it is possible to scrutinize SACD and CSSS with objectivity using appropriate methods of analytical morphology. These procedures apply to a series of clinical conditions including xerosis grading, comedometry, corneodynamics, corneomelametry, corneosurfametry, corneoxenometry, and dandruff assessment.ResultsWith any of the analytical evaluations, SACD and CSSS provide specific salient information that is useful in the field of cosmetology. In particular, both methods appear valuable and complementary in assessing the human skin compatibility of personal skincare products.ConclusionA set of quantitative analytical methods applicable to the minimally invasive and low-cost SACD and CSSS procedures allow for a sound assessment of cosmetic effects on the stratum corneum. Under regular conditions, both methods are painless and do not induce adverse events. Globally, CSSS appears more precise and informative than the regular SACD stripping.

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Skin protection creams in medical settings: successful or evil?

Cited by 17 publications

References 32 publications

VOC Contamination in Hospital, from Stationary Sampling of a Large Panel of Compounds, in View of Healthcare Workers and Patients Exposure Assessment

VOC Contamination in Hospital, from Stationary Sampling of a Large Panel of Compounds, in View of Healthcare Workers and Patients Exposure Assessment

Quick Guide to Contact Dermatitis

From observational to analytical morphology of the stratum corneum: progress avoiding hazardous animal and human testings

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