Urinary Tract Infections Caused by Staphylococcus saprophyticus and their antimicrobial sensitivity pattern in Young Adult Women

Abstract

The present study was conducted to observe the antibiotic sensitivity pattern of isolated S. saprophyticus from urine samples of patients admitted in inpatient department or visited the out patient department of Sir Salimullah Medical College & Mitford Hospital (SSMC& MH) Dhaka from October 2002 to September 2003. Among the isolates, Esch. coli was the most predominant (82.61%) urinary pathogens followed by S. saprophyticus (7.01%). 93.10% S. saprophyticus was isolated from females of which highest (44.82%) rate of isolation was among female of 18-45 years age group. Rate of isolation was also high (41.38%) among female of <18 years age group. All strains of S. saprophyticus (100%) were sensitive to Imipenem. High sensitivity was also observed to gentamicin (86.20%) and ceftriaxone (72.41%). Ciprofloxacin was found to be sensitive against 68.96% isolates. Sensitivity of ceftazidime, cephalexin and cloxacillin were 65.51%, 55.17% and 55.17% respectively. However, most of the S. saprophyticus are resistant to ampicillin, nalidixic acid and cotrimoxazole. So, the present study illustrates that physicians and microbiologists must be aware that S saprophyticus is an important cause of UTIs in young women and there is a need for continuous evaluation of common antibiotics used in the therapy of uropathogens.

Spectrum and Antibiotic Resistance Pattern of Bacteria Causing Urinary Tract Infections (UTI) in a Tertiary Care Hospital

“…(7.9%) was found second most common bacterial isolate, which correlates with other studies too. 29,30 In contrary to our findings, some studies reported Klebsiella spp. as second common isolate.…”

Evaluation of antimicrobial resistance pattern of uropathogens in a tertiary care hospital in Dhaka city, Bangladesh

“…Similar study in Bangladesh was previously reported by Jhora et al, who found the predominant isolated uropathogen was Escherichia coli 82.61% and others were Staphylococcuss saprophyticus 7.01%, Klebsiella 3.86%, Pseudomonas 3.14%, Proteus 1.45%, Staphylococcus aureus 0.24%. 26 A study from Kathmandu, Nepal showed that Escherichia coli was the most prevailing organism (81.3%). 27 Another study done in India where Escherichia coli was 31.25%, Pseudomonas 15.62%, Proteus 15.62%, Klebsiella 6.25% which did not correlate with our findings.…”

Prevalent Bacteria and Their Sensitivity and Resistance Pattern to Antibiotics: A Study in Dhaka Medical College Hospital

“…Again, most of the studies done in Bangladesh, concentrate on a single disease, pathogen, or specimen. [37][38][39][40][41][42][43][44][45][46][47][48][49][50][51] But, a single organism can cause different types of infection, at different sites and can cause different diseases. For example, E. coli can cause gastroenteritis, sepsis, UTI, even meningitis.…”