2009
DOI: 10.1016/j.jvs.2008.12.025
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Unmasking pedal arteries in patients with critical ischemia using time-resolved contrast-enhanced 3D MRA

Abstract: In our prospective study, t3D MRA has been proven to be superior to DSA and US scan in pedal vasculature imaging in critical limb ischemia. This is a valuable, noninvasive method for detecting potential pedal bypass target arteries.

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Cited by 26 publications
(11 citation statements)
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“…In addition, the present study also reveals excellent diagnostic capability of T-MTA in assessing significant stenosis for different portions of the lower limbs with an overall high sensitivity (99.5%), specificity (93.6%), PPV (95.4%), NPV (99.6%), and accuracy (97.7%). Concurrent with prior reports that suboptimal filling of distal vessels in DSA could lead to nonopacification of patent pedal arteries [912], six of our cases with target pedal arteries not visualized on DSA were depicted on T-MRA, enabling the subsequent successful surgical bypass grafting. This study confirms that the 3D three-station T-MRA at 3-tesla is a robust and an accurate method for assessing the entire vascular tree of patients with CLI, even though 75% of our patients had Fontaine stage IV lesions.…”
Section: Discussionsupporting
confidence: 77%
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“…In addition, the present study also reveals excellent diagnostic capability of T-MTA in assessing significant stenosis for different portions of the lower limbs with an overall high sensitivity (99.5%), specificity (93.6%), PPV (95.4%), NPV (99.6%), and accuracy (97.7%). Concurrent with prior reports that suboptimal filling of distal vessels in DSA could lead to nonopacification of patent pedal arteries [912], six of our cases with target pedal arteries not visualized on DSA were depicted on T-MRA, enabling the subsequent successful surgical bypass grafting. This study confirms that the 3D three-station T-MRA at 3-tesla is a robust and an accurate method for assessing the entire vascular tree of patients with CLI, even though 75% of our patients had Fontaine stage IV lesions.…”
Section: Discussionsupporting
confidence: 77%
“…The feasibility of T-MRA at 1.5-tesla for assessing patients with PAOD has been previously advocated in several studies [811]. In addition, some researchers have described promising studies of T-MRA focusing in the assessment of infrapopliteal or pedal vessels [12, 13]. InterSociety Consensus for the Management of Peripheral Arterial Disease (TASC II) provided the most important guidelines for the vascular surgeons in the treatment decision of PAOD [1].…”
Section: Introductionmentioning
confidence: 99%
“…Moreover, in 23% of the cases, 3D MR angiography detected flow that angiography did not (14). Similarly, in a separate study on pedal vascular imaging, 3D MR angiography was shown to offer a better representation of the CLI anatomy in the calf and pedal regions than DSA, and even afforded sub-millimeter voxel views (15). Furthermore, the recent introduction of blood pool MR angiography contrast agents have provided a more robust assessment of smaller vessels when compared to the more quickly cleared magnetic resonance imaging (MRI) contrast agents such as gadopentetate dimeglumine (Magnovist, Bayer, Leverkusen, Germany).…”
Section: Mr Angiographymentioning
confidence: 86%
“…This pulse sequence has the ability to acquire images through a volume of tissue throughout the passage of a single contrast bolus [13]. This ensures the acquisition of images which demonstrate the peak level of arterial Oblique coronal fast spin echo MR image of the ankle demonstrates a triangular 1.0×0.5 cm low signal intensity foreign body (arrow) medial to the base of the lesion, later confirmed to represent a retained glass fragment enhancement, while maintaining high sensitivity and specificity for arterial occlusive disease that is comparable to DSA [12,15,16]. In addition, information obtained from the bolus transit time can indirectly reflect flow rate.…”
Section: Discussionmentioning
confidence: 99%