UJI TOKSISITAS DAN IDENTIFIKASI AWAL GOLONGAN SENYAWA AKTIF EKSTRAK ETANOL DAN N-HEKSANA TERIPANG PASIR (Holothuria scabra) KERING PANTAI KENJERAN SURABAYA

Inayah, Nurul; Ningsih, Rachmawati; Adi, Tri Kustono

doi:10.18860/al.v0i0.2292

Cited by 7 publications

(7 citation statements)

References 7 publications

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“…Srivikaya et al menuliskan dalam hasil penelitiannya bahwa senyawa yang berperan sebagai penyembuh luka yaitu alkaloid dan saponin [13]. Sedangkan menurut Nurul et al dan Wijaya et al senyawa terpenoid berperan sebagai antioksidan dan antimikroba yang membantu dalam penyembuhan luka [9,16]. Penelitian Desiyana et al juga menyebutkan bahwa senyawa flavonoid dan tanin dapat berperan sebagai penyembuh luka [4].…”

Section: Hasil Dan Pembahasanunclassified

Potensi Ekstrak Biji Pala (Myristica fragrans L) Terhadap Penyembuhan Luka Bakar pada Mencit (Mus musculus)

Abdulkadir,

Djuwarno,

Ramadani Putri Papeo

et al. 2023

JSSCR

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The Nutmeg Plant (Myristica Fragrans L) is one of the spices plants empirically used as a therapeutic option for injury healing. Burn injury is damage to the skin's integrity caused by contact with a source with a high-temperature difference. This research aimed to determine the effectiveness of Nutmeg (Myristica Fragrans L) Seed extract on burn injury healing in Male Mice (Mus Musculus). Extraction was carried out through Maceration with Methanol solvent. Eighteen mice were divided into 6 groups: negative control (Na-CMC), positive control (Bioplacenton), and treatment groups with concentrations of 3%, 5%, 7%, and 10%. Burn injury was created using a 2 cm x 2 cm iron plate on the mice's back, and the healing of the burn injury diameter was observed from day 1 to day 20, with observation intervals at day 5, 10, 15, and 20. The data were analyzed using one-way ANOVA followed by an LSD test to determine the differences between test groups. The resalts indicate that the ethanol extract of Nutmeg (Myristica Fragrans L) see haseng effect on burn injury, with the most effective concentration being the extraet onoration of 10%, with a burn injury healing rate of up to 89,15%.

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Section: Hasil Dan Pembahasanunclassified

Potensi Ekstrak Biji Pala (Myristica fragrans L) Terhadap Penyembuhan Luka Bakar pada Mencit (Mus musculus)

Abdulkadir,

Djuwarno,

Ramadani Putri Papeo

et al. 2023

JSSCR

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“…Some of the compounds contained in sea cucumbers have been scientifically proven to have antioxidant properties that could reduce free radicals and prevent various degenerative diseases caused by excess free radicals. Compounds contained in sea cucumbers include lectins [19], sterols, tri-terpene glycosides [20], chondroitin, chondroitin sulfate E [21], vitamin B1, B2, B6, A, C, D, and E, amino acids, fatty acids (myristate, palmitate, stearic, docosahexesaenate (DHA), eicosapentaenate (EPA), etc. ), carotenoids, flavonoid compounds and polyphenols.…”

Section: Antioxidant Activitymentioning

confidence: 99%

Preparation of Sea Cucumber (Holothuria scabra) Powder: Effect of Pre-treatment on Its Nutritional, Antioxidant Activity and Morphological Characteristics

Ansharullah¹,

Patadjai²,

Asranudin³

et al. 2022

Advances in Biological Sciences Research

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Sea cucumber (Holothuria scabra) has a prospect of being one of the nutritious ingredients because it contains complete nutrients, including carbohydrates, essential fatty acids and amino acids, as well as several bioactive components that are believed to have functions as antioxidants, antibacterial, anti-fungal, and anticoagulant. The application of sea cucumber products in the food formulation may be expanded if it is made in the form of powder. This study was aimed to evaluate the application of three pre-treatment in preparing sea cucumber powder, and evaluated the effects on its nutritional content, antioxidant activity, and morphological properties. Three different types of ingredients, namely yam (Dioscorea hispidia Dennst) tuber extract, NaHCO3 solution, and papaya leaf extract, were added to the fresh sea cucumbers. Then, they were heated at 70 o C for 20 minutes in sea water, smoked, dried, and ground into powder. The results showed that the nutritional content of sea cucumber flour that was given papaya leaves extract had a higher protein content (59.33%) and higher ash content (14.71%) compared to the other treatments. The pre-treatment with papaya leaves extract had also given the strongest antioxidant activity. The morphological characteristics were observed with Scanning Electron Microscope (SEM).

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“…Pengamatan dilakukan selama 24 jam terhadap kematian larva udang. Perhitungan LC50 dilakukan menggunakan analisis probit menggunakan SPSS 20 dengan tingkat kepercayaan 95% [15].…”

Section: Uji Toksisitas Terhadap Larva Udangunclassified

Identifikasi dan Uji Toksisitas terhadap Larva Udang (Artemia salina L.) Ekstrak Bekatul Menggunakan Variasi Jenis Pelarut dan Lama Ekstraksi

Jannah

Maunatin

Jannah

2020

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Rice bran was extracted using ultrasonic method with varied solvents (ethanol, ethyl acetate and n-hexane) and extraction times (20, 25 and 30 minutes). The aim of this study was to determine toxicity value of rice bran extract with variation of solvents and extraction times. Rice bran extracts were tested its toxicity by BSLT method and its secondary metabolite by phytochemical test with reagents. Mortality data of shrimp larvae was analyzed by probit to determine LC50 values. Yield of ethanolic extract of rice bran for E1-20, E1-25 and E1-30 samples was 18.159, 19.132 and 18.280%, respectively. Rice bran extracts by ethyl acetate solvent (E2) and n-hexane (E3) gave different yields such as 8.302% (E2-20), 7.282% (E2-25), 9.18% (E2-30), 7.815% (E3-20), 7.125% (E3-25), and 7.279% (E3-30). All of rice bran extracts contained flavonoids, steroids and triterpenoids. LC50 values in ethanolic extract of rice bran for E1-20, E1-25 dan E1-30 samples were 613.258, 673.210 and 2217.255 ppm, respectively. Toxicity (LC50) values of ethyl acetate extract of rice bran were 1161.298 ppm (E2-20), 1170.774 ppm (E2-25) and 701.532 ppm (E2-30), while toxicity (LC50) values of n-hexane extract of rice bran were 592.901 ppm (E3-20), 617.425 ppm (E3-25) and 695.198 ppm (E3-30). Keywords: Rice bran, secondary metabolite, toxicity, ultrasonic method Bekatul diekstrak menggunakan metode ultrasonik dengan variasi pelarut (etanol, etil asetat dan n-heksana) dan lama ekstraksi (20, 25 dan 30 menit). Tujuan penelitian ini adalah mengetahui nilai toksisitas ekstrak bekatul dengan variasi pelarut dan lama ekstraksi. Ekstrak bekatul diuji kemampuan toksisitas terhadap larva udang dengan metode BSLT dan diuji fitokimia dengan reagen. Data kematian larva udang dianalisis dengan analisis probit untuk menentukan nilai LC50. Rendemen ekstrak etanol bekatul yang diperoleh pada sampel E1-20, E1-25 dan E1-30 masing-masing sebesar 18,159; 19,132; dan 18,280%. Adapun rendemen ekstrak etil asetat dan n-heksana bekatul sebesar 8,302% (E2-20), 7,282% (E2-25), 9,18% (E2-30), 7,815% (E3-20), 7,125% (E3-25) dan 7,279% (E3-30). Senyawa metabolit sekunder yang terkandung pada masing-masing ekstrak adalah flavonoid, steroid dan triterpenoid. Nilai LC50 ekstrak etanol pada masing-masing sampel E1-20, E1-25 dan E1-30 adalah 613,258; 673,210 dan 2217,255 ppm. Ekstrak etil asetat bekatul pada sampel E2-20, E2-25 dan E2-30 memberikan nilai toksisitas dengan LC50 sebesar 1161,398; 1170,774 dan 701,532 ppm, berturut-turut. Nilai toksisitas (LC50) ekstrak n-heksana pada sampel E3-20, E3-25 dan E3-30 adalah 592,901; 617,425 dan 695,198 ppm, berturut-turut. Kata kunci: Bekatul, metabolit sekunder, toksisitas, metode ultrasonik

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UJI TOKSISITAS DAN IDENTIFIKASI AWAL GOLONGAN SENYAWA AKTIF EKSTRAK ETANOL DAN N-HEKSANA TERIPANG PASIR (Holothuria scabra) KERING PANTAI KENJERAN SURABAYA

Cited by 7 publications

References 7 publications

Potensi Ekstrak Biji Pala (Myristica fragrans L) Terhadap Penyembuhan Luka Bakar pada Mencit (Mus musculus)

Potensi Ekstrak Biji Pala (Myristica fragrans L) Terhadap Penyembuhan Luka Bakar pada Mencit (Mus musculus)

Preparation of Sea Cucumber (Holothuria scabra) Powder: Effect of Pre-treatment on Its Nutritional, Antioxidant Activity and Morphological Characteristics

Identifikasi dan Uji Toksisitas terhadap Larva Udang (Artemia salina L.) Ekstrak Bekatul Menggunakan Variasi Jenis Pelarut dan Lama Ekstraksi

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