Uji Kandungan Senyawa Metabolit Sekunder pada Ekstrak Daun Jambu Biji (Psidium guajava L var. Pomifera) dari Kota Langsa, Aceh

Simbolon, Reni Aisyah; Halimatussakdiah, Halimatussakdiah; Amna, Ulil

doi:10.33059/jq.v3i1.3493

Cited by 6 publications

(6 citation statements)

References 10 publications

(23 reference statements)

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“…Phytochemical Results. The bioactive components of the extract were flavonoids, tannins, steroid saponins, total phenol (6.08%, quercetin 0.31 mg, and antioxidant activity >31.25 ppm in a mixed section of Psidium guajava L. Melastoma malabathricum L. Additional research has shown alkaloids, flavonoids, saponins, tannins, terpenoids (20) , alkaloids, steroids, saponins, phenols, and tannins (21) . Melastoma candidum D. Don contains flavonoids, triterpenoids, steroids, saponins, tannins, and glycosides (26) .…”

Section: Resultsmentioning

confidence: 91%

Diabetic Wound Healing and Antimicrobial Activities of Gels Melastoma malabathricum L. and Psidium guajava L. in Sprague Dawley Rats

Refdanita,

Maigoda,

Firdaus

et al. 2023

jifi

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Diabetes mellitus (DM) is a degenerative disease characterized by abnormalities in carbohydrate, lipid, and protein metabolisms. This research was aimed at the gel’s pharmacological activity, the extract’s potential in treating diabetic wounds in male rats of Melastoma malabathricum L leaves (ML) and Psidium guajava L leaves (PL), as well as microbiological activity. Viscous extracts of ML and PL were prepared in gel dosage form with concentrations of 4% and 6%. Clindamycin was used as a positive control. This study was conducted using an experimental laboratory method, and the study population included white male rats. The pharmacological activity was tested in the form of a gel dosage formula, and the rats were made diabetic using alloxan. The potential of the extract was observed in healing diabetic wounds in male rats. ML and PL leaf extract gels affect wound healing in diabetic patients. This can be seen from the change in diameter. Wound swab examination revealed the presence of bacteria Klebsiella pneumoniae and Staphylococcus aureus. Secondary metabolites of flavonoids, tannins, steroids, and saponins help stimulate the regeneration of epithelial cells and tissues. The results for wound healing of 4% and 6% gel formulations were derived from maturation data on day 10.

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Section: Resultsmentioning

confidence: 91%

Diabetic Wound Healing and Antimicrobial Activities of Gels Melastoma malabathricum L. and Psidium guajava L. in Sprague Dawley Rats

Refdanita,

Maigoda,

Firdaus

et al. 2023

jifi

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“…Tanaman daun jambu biji (Psidium guajava L.) merupakan salah satu tanaman yang berkhasiat dan memiliki banyak manfaat. Kandungan dalam daun jambu biji seperti saponin, tanin, flavonoid, dan alkaloid memiliki sifat antibakteri dan antioksidan [6].…”

Section: Pendahuluanunclassified

“…Berdasarkan hasil pengamatan organoleptik setelah dilakukan cycling test selama 12 hari (6 siklus), pada formula 1 dan 2 terjadi perubahan warna hijau pekat kecoklatan yaitu pada siklus ke 5 dan ke 6…”

Section: Hasil Evaluasi Uji Stabilitasunclassified

Pengaruh Variasi Konsentrasi Dinatrium EDTA Terhadap Stabilitas Fisika dan pH Sediaan Salep Ekstrak Etanol Daun Jambu Biji (Psidium guajava L.)

Rizkuloh

Adlina

Yuliana

2023

MPI

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Daun jambu biji (Psidium guajava L.) merupakan salah satu tanaman yang berkhasiat, karena mengandung metabolit sekunder saponin, tanin, flavonoid, serta alkaloid. Senyawa-senyawa tersebut memiliki sifat antibakteri. Kandungan antibakteri pada daun jambu biji ini menjadi dasarpengembangan sediaan dalam bentuk salep yang berkhasiat sebagai antibakteri dengan memvariasikan salah satu bahan sebagai penstabil yaitu dinatrium EDTA. Tujuan dari penelitian ini adalah mengetahui pengaruh konsentrasi dinatrium EDTA tehadap stabilitas fisika sediaan salep ekstraketanol daun jambu biji (Psidium guajva L.). Dalam penelitian ini dibuat 3 formula dengan variasi konsentrasi dinatrium EDTA yaitu F1 (0,05%); F2 (0,08%) serta F3 (0,10%). Evaluasi stabilitas fisik sediaan salep dilakukan selama 12 hari (6 siklus), meliputi uji organoleptik, uji homogenitas, uji pH, uji daya lekat, uji daya sebar dan uji stabilitas. Hasil pengamatan organoleptik selama cycling test menunjukan adanya perubahan warna pada sediaan yaitu pada siklus ke 5 dan 6. Selain itu, dengan bertambahnya konsentrasi dinatrium EDTA berpengaruh terhadap pH. Semakin tinggi konsentrasi dinatrium EDTA maka semakin kecil pH dan berpengaruh pada stabilitas fisika sediaan. Hasil menunjukan bahwa sediaan yang stabil dan memenuhi syarat yaitu formula 3 dengan konsentrasi dinatrium EDTA 0,10 %. Guava leaves (Psidium guajava L.) is one of the efficacious plants, because it contains secondary metabolites of saponins, tannins, flavonoids, and alkaloids; where these compounds have antibacterial properties. With the presence of antibacterial content in guava leaves, a preparation was made in the form of an antibacterial ointment by varying one of the ingredients as a stabilizer, namely disodium EDTA. The purpose of this study was to determine the effect of disodium EDTA concentration on the physical stability of the ethanol extract ointment of guava leaves (Psidium guajva L.). In this study, 3 formulas were prepared with variations in the concentration of disodium EDTA, namely F1 (0.05%); F2 (0.08%) and F3 (0.10%), respectively. Evaluation of the physical stability of the ointment was carried out for 12 days (6 cycles), including organoleptic tests, homogeneity tests, pH tests, adhesion tests, spreadability tests and stability tests. The results of organoleptic observations during the cycling test showed that there was a change in the color of the preparation in the 5th and 6th cycles. In addition, increasing the disodium EDTA concentration affected the pH, where the higher the disodium EDTA concentration, the lower the pH and affected the physical stability of the preparation. The results showed that the preparation that met the requirements for ointment stability was formula 3 with a concentration of 0.10% disodium EDTA.

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“…Tanin yang mengandung lebih banyak gugus hidroksil cenderung menghasilkan endapan biru kehitaman (Halimu et al, 2017). Tanin diketahui memiliki berbagai manfaat, termasuk astringen, antidiare, antibakteri, dan antioksidan (Simbolon et al, 2021). Tanin berfungsi sebagai antioksidan biologis yang dapat mengendapkan protein (Kurniawan & Zahra, 2021).…”

Section: Ekstrak Batang Kemangi Yang Ditambahkan Dengan Pereaksiunclassified

IDENTIFIKASI SENYAWA METABOLIT SEKUNDER PADA EKSTRAK METHANOL BATANG KEMANGI (Ocimum bacilicum L)

Andiarna,

Kumalasari,

Tyastirin

et al. 2023

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Tanaman kemangi (Ocimum bacilicum L) adalah salah satu tanaman obat tradisional yang paling banyak dikembangkan di negara Indonesia. Tanaman kemangi memiliki banyak manfaat seperti mengobati demam, diare, batuk, pusing, mual, dan lain sebagainya. Tujuan dari penelitian ini untuk mengidentifikasi senyawa metabolit sekunder pada batang tanaman kemangi. Ekstrak kemangi menggunakan pelarut metanol 96%. Batang daun kemangi dilakukan proses penyarian dengan metode maserasi. Ekstrak kemangi selanjutnya dilakukan uji fitokimia untuk mengetahui kandungan senyawa metabolit sekunder. Hasil dari penelitian ini menunjukkan bahwa pada batang tanaman kemangi terdapat kandungan senyawa metabolit sekunder yaitu flavonoid, tannin, alkaloid dan saponin. Hal ini dapat menjelaskan bahwa ekstrak kemangi memiliki potensi yang kuat dalam aktivitas antioksidan yang memiliki peran penting dalam pemanfaatan obat tradisional. Senyawa flavonoid paling umum dijadikan sebagai antioksidan. Selain itu beberapa jenis senyawa alkaloid, tanin dan saponin juga mempunyai efek antioksidan. Kata Kunci: Kemangi, Metanol, Ocimum bacilicum L, Senyawa metabolit sekunder The basil plant (Ocimum bacilicum L) is one of Indonesia's most developed traditional medicinal plants. Basil plants have many benefits, such as treating fever, diarrhea, cough, dizziness, nausea, etc. The study aims to identify secondary metabolite compounds in the stem of basil plants. Basil extract uses 96% methanol solvent. Stems of basil leaves carried out the process of expulsion by maceration method. The phytochemical test was conducted through basil extraction to determine the secondary content of metabolite compounds. The results of this research show that the stem of the basil plant is a secondary metabolite compound, namely flavonoids, alkaloids, tannins, and saponins. It can explain that basil extract has a strong potential for antioxidant activity that has an essential role in traditional medicine. Keywords: Methanol, Ocimum bacilicum, Secondary metabolites compounds, Stem basil

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Uji Kandungan Senyawa Metabolit Sekunder pada Ekstrak Daun Jambu Biji (Psidium guajava L var. Pomifera) dari Kota Langsa, Aceh

Cited by 6 publications

References 10 publications

Diabetic Wound Healing and Antimicrobial Activities of Gels Melastoma malabathricum L. and Psidium guajava L. in Sprague Dawley Rats

Diabetic Wound Healing and Antimicrobial Activities of Gels Melastoma malabathricum L. and Psidium guajava L. in Sprague Dawley Rats

Pengaruh Variasi Konsentrasi Dinatrium EDTA Terhadap Stabilitas Fisika dan pH Sediaan Salep Ekstrak Etanol Daun Jambu Biji (Psidium guajava L.)

IDENTIFIKASI SENYAWA METABOLIT SEKUNDER PADA EKSTRAK METHANOL BATANG KEMANGI (Ocimum bacilicum L)

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