Two new rotenoids from the root of Derris elliptica

Isoflavonoids of the Leguminosae

“…In contrast, the open C-ring structure of the seco-rotenoid, elliptol (139), results from cleavage of the bond between C-6a and O-7. 143 Root extracts of D. elliptica also afforded a derivative of 6a,12a-dehydrodeguelin characterised by hydroxylation of one of the gem-dimethyl groups of the pyran E-ring (140), 149 a 5 0 -epimer of 6a,12a-dehydroderrisin (142), 150 and a 4 0 -epimer of 11-hydroxy-6a,12a-dehydroderrisin (143). 150 A study of rotenoid constituents of Derris malaccensis roots has provided the rst fully veried occurrence of 6a,12adehydroelliptone (144) as a natural product.…”

“…143 Root extracts of D. elliptica also afforded a derivative of 6a,12a-dehydrodeguelin characterised by hydroxylation of one of the gem-dimethyl groups of the pyran E-ring (140), 149 a 5 0 -epimer of 6a,12a-dehydroderrisin (142), 150 and a 4 0 -epimer of 11-hydroxy-6a,12a-dehydroderrisin (143). 150 A study of rotenoid constituents of Derris malaccensis roots has provided the rst fully veried occurrence of 6a,12adehydroelliptone (144) as a natural product. 151 Previously it was known only as a synthetic product, 151 although an unconrmed report refers to its detection in Derris elliptica.…”

Assessment of population genetic diversity of Derris elliptica (Fabaceae) in China using microsatellite markers

“…(Fabaceae) is commonly used in traditional medicine (Sukrong et al, 2006). Juice from its stems and roots is used as an insecticide (Andrea et al, 2007), molluscicide (Dos Santos and Sant'Ana, 2000) and fish poison (Lu et al, 2008). Some other bioactive properties, such as antifungal (Fang et al, 2010), antihypertension effect (Dos Santos and Sant'Ana, 2000) and antitumor activity (Chun et al, 2003) have also been confirmed.…”

“…Some other bioactive properties, such as antifungal (Fang et al, 2010), antihypertension effect (Dos Santos and Sant'Ana, 2000) and antitumor activity (Chun et al, 2003) have also been confirmed. The plant is mainly cultivated in the tropics for its roots, a source of the botanical insecticide rotenone (Andrea et al, 2007;Lu et al, 2008;Wu et al, 2012b). In China, D. elliptica was introduced from different Southeast Asian countries beginning in the early decades of the last century (Li and Wang, 2010), and was mainly cultivated in Guangdong and Guangxi Provinces as a raw material for the commercial manufacture of rotenone.…”

Evaluation of cytotoxicity and genotoxicity of some Philippine medicinal plants

“…[ 2 ] Various rotenoids were isolated from its roots. [ 3 5 ] There are no reports regarding the biological activity of Ficus elastica. Morus alba is used as a traditional medicine in several countries like Italy and Tunisia,[ 6 ] Jordan,[ 7 ] Korea[ 8 ] and India.…”