Two New 4‐Hydroxyisoflavanes from the Root of <i>Codonopsis cordifolioidea</i> and Their Anti‐virus Activities

Mu, Haibo; Li, Xuesen; Yang, Guang–Yu; Li, Gan‐Peng; Hu, Qiu‐Fen

doi:10.1002/jccs.201100525

Cited by 14 publications

(9 citation statements)

References 8 publications

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“…Since certain isoflavones exhibit potential anti-TMV activity (Chen et al, 2012b;Gao et al, 2012b;Hu et al, 2013b), compounds 1-3 were tested for their anti-TMV activities. The inhibitory activities of compounds 1-6 against TMV replication were tested using the half-leaf method (Hu et al, 2013a).…”

Section: Resultsmentioning

confidence: 99%

Isoflavones from the leaves of Nicotiana tabacum and their anti-tobacco mosaic virus activities

Shen

Liu

et al. 2015

Phytochemistry Letters

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Section: Resultsmentioning

confidence: 99%

Isoflavones from the leaves of Nicotiana tabacum and their anti-tobacco mosaic virus activities

Shen

Liu

et al. 2015

Phytochemistry Letters

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“…The compound 1 was thus deduced as show and given the name as gramphenol A. Since some of the phenolic compounds exhibited anti virus activities 10,11 compounds 1-4 were tested for the antitobacco mosaic virus activity using the half-leaf method according to literature 12 .…”

Section: Resultsmentioning

confidence: 99%

Phenolic Compounds from Arundina graminifolia and Their Anti-Tobacco Mosaic Virus Activities

ZeRui¹,

Xu²,

Wei³

et al. 2013

Asian J. Chem.

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to Indonesia and across the Pacific Islands. The genus is considered to possess activities of detoxification, antiarthritis and abirritation and is used as antidote and demulcent 1. In recent years, several papers have described phytochemistry investigations of A. gramnifolia and was found to be rich in stilbenoids and triterpenes 2-5. Motivated by a search for bioactive compounds from this plant, further chemical investigation were carried out. As a result, a new phenolic compounds (1), together with three known phenols (2-4), were isolated from this plant. In addition, the antitobacco mosaic virus activities of compounds 1-4 were evaluated. This article deals with the isolation, structural elucidation and biological activities of the isolated compounds. EXPERIMENTAL Optical rotations were measured with a Horiba SEPA-300 polarimeter. UV spectra were obtained using a Shimadzu UV-2401A spectrophotometer. A Tenor 27 spectrophotometer was used for scanning IR spectroscopy with KBr pellets. 1 D and 2 D NMR spectra were recorded on DRX-500 spectrometers with TMS as internal standard. Unless otherwise specified, chemical shifts (δ) were expressed in ppm with reference to the solvent signals. HRESIMS was performed on an API QSTAR time-of-flight spectrometer and a VG autospec-3000 spectrometer, respectively. Preparative HPLC was performed

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“…(3R) 7,2′,4′-Trihydroxy-3′-methoxy-5-methoxycarbonylisoflavanone (205) was the most active among the tested compounds [102]. In addition to anti-TMV, cordifoliflavanes A (236) cordifoliflavanes B (237) expressed anti-HIV-1 activities [109].…”

Section: Flavonoids -From Biosynthesis To Human Healthmentioning

confidence: 99%

Isoflavonoids

Foudah¹,

Abdel-Kader²

2017

Flavonoids - From Biosynthesis to Human Health

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Isoflavonoids are interesting class of natural products due to their positive effects on human health. Isoflavonoids include isoflavones, isoflavanones, isoflavans, rotenoids and pterocarpans. Although they are reported from many plant families, most isoflavonoids are produced by the subfamily Papilionaceae of the Fabaceae. Various chromatographic methods have been applied for the purification of isoflavonoids. Simple Ultra Violet (UV) absorption spectra as well as both One and two dimensional NMR (1D-and 2D-NMR) are critical for the identification of isoflavonoids. Each class of isoflavonoids has its unique feature in both 1 H-and 13 C-NMR that enable their proper characterization. High Resolution Mass Spectrometry (HRMS) is a substantial tool in such challenge. In vitro experiments indicated that isoflavonoids possess antioxidant, antimutagenic, antiproliferative as well as cancer preventive effects. Epidemiological studies provide support for some of these effects on human. Members of this class also are reported to have antimicrobial activity. In this chapter, isoflavones, isoflavanones, isoflavans, homoisoflavonoids and isoflavenes will be discussed in relation to their occurrence, methods of purification, spectral characters helpful in structure elucidation as well as their biological importance.

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Two New 4‐Hydroxyisoflavanes from the Root of Codonopsis cordifolioidea and Their Anti‐virus Activities

Cited by 14 publications

References 8 publications

Isoflavones from the leaves of Nicotiana tabacum and their anti-tobacco mosaic virus activities

Isoflavones from the leaves of Nicotiana tabacum and their anti-tobacco mosaic virus activities

Phenolic Compounds from Arundina graminifolia and Their Anti-Tobacco Mosaic Virus Activities

Isoflavonoids

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