Tumors of cutaneous appendages

Weedon, David

doi:10.1016/b978-0-7020-3485-5.00034-6

Cited by 67 publications

(126 citation statements)

References 1,508 publications

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“…[11][12][13] Trichoblastoma (TB) is extremely rare benign tumors located deep dermis and subcutis. 14 It is frequently seen on head and neck 3,15 and mostly sized less than 1 cm in diameter.…”

Section: Introductionmentioning

confidence: 99%

“…Ackerman et al criticised the classifications, used in eight textbooks of dermatopathology in 2001. 3,4 Tumors of cutaneous appandages originating from hair follicle was seperated into two main subgroups as benign tumors and malignant tumors according to 2003 Classification of World Health Organization (WHO). 1 Trichoadenoma (TA) is firstly determined by Nikolowski 5 in 1958 and is a rare tumor which is usually seen as a nodular lesion on the face and buttocks.…”

Section: Introductionmentioning

confidence: 99%

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Histopathological Characteristics may not be Useful in the Differential Diagnosis Between Basal Cell Carcinoma and Benign Tumors of Cutaneous Appandages Originating from Hair Follicle

Şengül¹

2011

UHOD

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Differential diagnosis between benign tumors of cutaneous appandages originating from hair follicle (BTCOHF) (trichoadenoma [TA], trichofolliculoma [TF], trichoepithelioma [TE] and trichoblastoma [TB]) and basal cell carcinoma (BCC) have been tedious for the pathologists, especially in the presence of small specimens to date. Thirty cases of BTCOHF and 30 cases of BCC were retrieved from the archives, deposited from 2004 to 2008. Age, sex, localisation and histopathological characters such as ulceration, pigmentation, inflammation, and cyst formation were comparatively evaluated between both groups and each subgroups. No significant diference was detetected between two groups in the rate of the age, sex and the histopathology. Besides, histopathological characters were not significant for the subgroups of BCC. However, ulceration was observed in TE (Of 21 cases 5, [23.8%]) and TB (All the 5 cases, [100%]), but not in TA and TF which are the subgroups of BTCOHF and the difference was significant (p= 0,005). But, pigmentation, inflammation and cyst formation were not significant among the subgroups of both groups. We can conclude that BCC and BTCOHF may not be discriminated concerning age, sex and histopathological characters including ulceration, pigmentation, inflammation, and cyst formation. Secondly, one may not make the differential diagnosis easily even between the subgroups of each group via evaluating the histopathological characters, so that might create some life-threatening unwelcome outcomes. Keywords: Basal cell carcinoma, Pigmentation, Inflammation, Histopathology ÖZET Histopatolojik karakterler Bazal Hücreli Karsinoma ile K›l Follikülünden Köken Alan Benign Deri Eki Tümörlerinin Ay›r›c› Tan›s›nda Yararl› OlamayabilirTrikoadenoma, trikofolliküloma, trikoepitelyoma ve trikoblastoman›n bazal hücreli karsinomadan ay›r›c› tan›s›, bugüne kadar özellikle küçük spesimenlerde patologlar için can s›k›c› ve usand›r›c› olmaya devam edegelmifltir. Otuz k›l follikülünden köken alan benign deri eki tümörleri olgusu ve 30 bazal hücreli karsinoma olgusu, 2004 -2008 y›llar› aras›nda depoland›¤› arflivden yeniden edinildi. Yafl, cinsiyet, lokalizasyon ve ülserasyon, pigmentasyon, inflamasyon ve kist formasyonu gibi histopatolojik karekterler her iki grup ve her subgrup aras›nda karfl›laflt›rmal› olarak de¤erlendirildi. Yafl, cinsiyet, lokalizasyon ve histopatoloji aç›s›ndan iki grup aras›nda anlaml› fark saptanmad›. Ayr›ca, histopatolojik karekterler bazal hücreli karsinoman›n subgruplar› için anlaml› de¤ildi. Bununla birlikte; ülse-rasyon, k›l follikülünden köken alan benign deri eki tümörlerinin subgruplar› olan trikoepitelyoma (21 olgunun 5'inde [%23.8]) ve trikoblastomada (5 olgunun tümünde [%100]) izlendi, ancak trikoadenoma ve trikofollikülomada izlenmedi ve bu fark anlaml› bulundu (p= 0.005). Pigmentasyon, inflamasyon ve kist formasyonu her iki grubun subgruplar› aras›nda anlaml› de¤ildi.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Histopathological Characteristics may not be Useful in the Differential Diagnosis Between Basal Cell Carcinoma and Benign Tumors of Cutaneous Appandages Originating from Hair Follicle

Şengül¹

2011

UHOD

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“…Selective lymph node dissection is often used. The value of adjuvant radiotherapy has not been confirmed [3]. As early recurrence is common despite the wide excision close follow-up is mandatory [2].…”

Section: Discussionmentioning

confidence: 99%

“…The cells express the high molecular weight cytokeratins CK5/6 and CK7, as well as p63, androgen receptor, estrogen receptor, and sometimes Her-2/neu. Ki-67 and p53 staining may be useful histologic parameters [3,6]. Even after the complete excision MNH has a potential for local recurrence, tends to metastasize, and often cause death [7].…”

Section: Discussionmentioning

confidence: 99%

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Malignant Nodular Hidradenoma of the Scalp: A Case Report

2017

Ann Clin Anal Med

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ÖzMalign nodüler hidradenoma (MNH) nadir bir deri eki tümörüdür. Kafa derisi bu tü-mör için alışılmadık lokalizasyonlardan biridir. Bu çalışmada, kafa derisinde yavaş büyüyen kitle ile başvuran ve histopatolojik değerlendirme sonucu malign nodüler hidradenom tanısı alan 80 yaşında kadın hastayı sunmayı amaçladık. MNH müm-kün olduğu kadar erken tanı alması ve cerrahi olarak geniş rezeksiyon yapılması gereken agresif bir tümördür. Buna karşın erken rekürrens sık olduğundan yakın klinik takip gerektirir. Anahtar KelimelerDeri Eki Tümörü; Kafa Derisi; Karsinom; Malign Nodüler Hidradenom AbstractMalignant nodular hidradenoma (MNH) is a rare sweat gland tumor of the skin.The scalp is an uncommon site of occurrence. We, herein, present an 80-year-old woman whose slow-growing subcutaneous nodule on her scalp was diagnosed as malignant nodular hidradenoma after histopathologic examination. MNH is an aggressive tumor and should be diagnosed and excised as early as possible. Wide local excision is the treatment of choice. As early recurrence is common despite the wide excision close follow-up is necessary.

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