Differential diagnosis between benign tumors of cutaneous appandages originating from hair follicle (BTCOHF) (trichoadenoma [TA], trichofolliculoma [TF], trichoepithelioma [TE] and trichoblastoma [TB]) and basal cell carcinoma (BCC) have been tedious for the pathologists, especially in the presence of small specimens to date. Thirty cases of BTCOHF and 30 cases of BCC were retrieved from the archives, deposited from 2004 to 2008. Age, sex, localisation and histopathological characters such as ulceration, pigmentation, inflammation, and cyst formation were comparatively evaluated between both groups and each subgroups. No significant diference was detetected between two groups in the rate of the age, sex and the histopathology. Besides, histopathological characters were not significant for the subgroups of BCC. However, ulceration was observed in TE (Of 21 cases 5, [23.8%]) and TB (All the 5 cases, [100%]), but not in TA and TF which are the subgroups of BTCOHF and the difference was significant (p= 0,005). But, pigmentation, inflammation and cyst formation were not significant among the subgroups of both groups. We can conclude that BCC and BTCOHF may not be discriminated concerning age, sex and histopathological characters including ulceration, pigmentation, inflammation, and cyst formation. Secondly, one may not make the differential diagnosis easily even between the subgroups of each group via evaluating the histopathological characters, so that might create some life-threatening unwelcome outcomes. Keywords: Basal cell carcinoma, Pigmentation, Inflammation, Histopathology ÖZET Histopatolojik karakterler Bazal Hücreli Karsinoma ile K›l Follikülünden Köken Alan Benign Deri Eki Tümörlerinin Ay›r›c› Tan›s›nda Yararl› OlamayabilirTrikoadenoma, trikofolliküloma, trikoepitelyoma ve trikoblastoman›n bazal hücreli karsinomadan ay›r›c› tan›s›, bugüne kadar özellikle küçük spesimenlerde patologlar için can s›k›c› ve usand›r›c› olmaya devam edegelmifltir. Otuz k›l follikülünden köken alan benign deri eki tümörleri olgusu ve 30 bazal hücreli karsinoma olgusu, 2004 -2008 y›llar› aras›nda depoland›¤› arflivden yeniden edinildi. Yafl, cinsiyet, lokalizasyon ve ülserasyon, pigmentasyon, inflamasyon ve kist formasyonu gibi histopatolojik karekterler her iki grup ve her subgrup aras›nda karfl›laflt›rmal› olarak de¤erlendirildi. Yafl, cinsiyet, lokalizasyon ve histopatoloji aç›s›ndan iki grup aras›nda anlaml› fark saptanmad›. Ayr›ca, histopatolojik karekterler bazal hücreli karsinoman›n subgruplar› için anlaml› de¤ildi. Bununla birlikte; ülse-rasyon, k›l follikülünden köken alan benign deri eki tümörlerinin subgruplar› olan trikoepitelyoma (21 olgunun 5'inde [%23.8]) ve trikoblastomada (5 olgunun tümünde [%100]) izlendi, ancak trikoadenoma ve trikofollikülomada izlenmedi ve bu fark anlaml› bulundu (p= 0.005). Pigmentasyon, inflamasyon ve kist formasyonu her iki grubun subgruplar› aras›nda anlaml› de¤ildi.
Context:Existence of non-inflamed or inflamed vermiform appendix in an inguinal hernia is named Amyand's hernia in honor to the surgeon Claudius Amyand who successfully performed first perforated appendicitis.Case Report:A 69-year-old Turkish male patient with a slight right groin pain and swelling was presented to our clinic, and found to have a slightly tender and reducible right inguinal hernia. He underwent surgery under general anesthesia, and a adhesive caecum and an inflamed appendix were explored within the hernia sac. Adhesions were divided by sharp dissection and appendectomy was performed. After carrying out a Lichtenstein hernioplasty, a broad-spectrum antibiotic was postoperatively admitted for 3 days. He recovered uneventfully, and neither complication nor recurrence was detected during 52 months of follow-up.Conclusions:Although occurrence of an appendicitis in an inguinal hernia is rare, a surgeon should be vigilant for facing with it even in elective cases. Treatment can be provided only surgically, but surgical treatment is not standard except from appendectomy. In our opinion, application of mesh hernia repair should depend on the degree of inflammation of appendix and the presence of incarceration of hernia sac with a suitable antibiotic admission for 3-5 days postoperatively.
Context:Pleomorphic adenoma is the most common neoplasm of the minor salivary glands which are uncommon among the entire salivary gland tumors. The lower lip is a very rare site of occurrence for pleomorphic adenoma. We intended to present a case of pleomorphic adenoma of the lower lip.Case Report:A 49-year-old Turkish man presented with the painless mass on his lower lip. A total excision was choiced for the mass by both we and the patient because of some cosmetic reasons. The histopathological evaluation revealed the diagnosis of pleomorphic adenoma and neither complication nor recurrence was observed during a clinical follow-up for 40 months.Conclusions:A clinician should be vigilant for the possibility of existence of a pleomorphic adenoma located on the lower lip even it is rare. Once it is diagnosed concisely, a wide excision is suggested in general if there is no cosmetic care and no risk of damage to functional structures of head and neck.
The aim of this study was to test the hypothesis that postconditioning (POC) would reduce the detrimental effects of the acute intestinal ischemia-reperfusion (I/R) compared to those of the abrupt onset of reperfusion. POC has a protective effect on intestinal I/R injury by inhibiting events in the early minutes of reperfusion in rats. Twenty-four Wistar-Albino rats were subjected to the occlusion of superior mesenteric artery for 30 minutes, then reperfused for 120 minutes, and randomized to the four different modalities of POC: (1) control (no intervention); (2) POC-3 (three cycles of 10 seconds of reperfusion-reocclusion, 1 minute total intervention); (3) POC-6 (six cycles of 10 seconds of reperfusion-reocclusion, 2 minutes total intervention); and (4) sham operation (laparotomy only). The arterial blood samples [0.3 mL total creatine kinase (CK) and 0.6 mL malondialdehyde (MDA)] and the intestinal mucosal MDA were collected from each after reperfusion. POC, especially POC-6, was effective in attenuating postischemic pathology by decreasing the intestinal tissue MDA levels, serum total CK activity, inflammation, and total histopathological injury scores. POC exerted a protective effect on the intestinal mucosa by reducing the mesenteric oxidant generation, lipid peroxidation, and neutrophil accumulation. The six-cycle algorithm demonstrated the best protection.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.