“…If the patient is asymptomatic no treatment is indicated. If the visual acuity drops, usually occurring in the third or fourth decade, several therapies have been advocated, such as argon laser treatment [7,8,18,30], radiation (external beam, photon irradiation, brachytherapy) [12,13,14,19,21,32,41,42], and hyperthermia (microwave thermo therapy, transpupillary thermotherapy) [9,10,11,16,25,28]. In 2000, Barbazetto and Schmidt-Erfurth used photodynamic therapy with verteporfin in two patients [6].…”