This article addresses the design, analysis, and parameterization of reconfigurable multi-band noise and signal transfer functions (NTF and STF), realized with multistage quadrature modulator (Q M) concept and complex-valued in-phase/quadrature (I/Q) signal processing. Such multi-band scheme was already proposed earlier by the authors at a preliminary level, and is here developed further toward flexible and reconfigurable A/D interface for cognitive radio (CR) receivers enabling efficient parallel reception of multiple noncontiguous frequency slices. Owing to straightforward parameterization, the NTF and the STF of the multistage Q M can be adapted to input signal conditions based on spectrum-sensing information. It is also shown in the article through closed-form response analysis that the so-called mirror-frequency-rejecting STF design can offer additional operating robustness in challenging scenarios, such as the presence of strong mirror-frequency blocking signals under I/Q imbalance, which is an unavoidable practical problem with quadrature circuits. The mirror-frequency interference stemming from these blockers is analyzed with a novel analytic closed-form I/Q imbalance model for multistage Q Ms with arbitrary number of stages. Concrete examples are given with three-stage Q M, which gives valuable degrees of freedom for the transfer function design. High-order frequency asymmetric multi-band noise shaping is, in general, a valuable asset in CR context offering flexible and frequency agile adaptation capability to differing waveforms to be received and detected. As demonstrated by this article, multistage Q Ms can indeed offer these properties together with robust operation without risking stability of the modulator.