Topical 5-aminolaevulinic acid photodynamic therapy for tumour-stage mycosis fungoides

Markham, Trevor; Sheahan, K.; Collins, Paul M.

doi:10.1046/j.1365-2133.2001.04245.x

Cited by 48 publications

(20 citation statements)

References 8 publications

(6 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…PDT has been successfully used in CTCL (MF and CD30 1 CTCL). [7][8][9][10][11][12] We treated 3 patients with early CBCL, with complete remission achieved in all 3 after a maximum of two PDT sessions. The successful use of ALA-PDT in indolent CBCL, to our knowledge reported herein for the first time, suggests a possible role of PDT in the treatment of localized, thin plaques as an alternative to local RT, which has to be considered the treatment of choice.…”

Section: Discussionmentioning

confidence: 99%

“…To date, other case series of MF patients (both in plaque and tumor stages) and 2 patients with CD30 1 cutaneous T-cell lymphoma (CTCL) successfully treated with PDT have been reported. [7][8][9][10][11][12][13][14][15] To date, no reports are available concerning the use of systemic or local PDT in the treatment of CBCL. We report herein about the successful ALA-PDT treatment of 3 patients with early CBCL.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Topical photodynamic therapy for primary cutaneous B-cell lymphoma: A pilot study

Mori¹,

Campolmi

Mavilia

et al. 2006

Journal of the American Academy of Dermatology

View full text Add to dashboard Cite

consider mycobacterial infections and inquire about recent pedicures in patients with apparent lowerextremity furunculosis. Tissue cultures and sensitivity studies should be performed to guide treatment, given the widespread antibiotic resistance of mycobacteria species. Early recognition of the organisms and institution of appropriate therapy are critical. Physicians and the public need to be educated about the possibility of infections following pedicures, and physicians should inquire about pedicures when faced with nonhealing furunculosis of the lower legs. Public health measures should be explored to protect against such infections given the recent increase in popularity of the nail care industry.

show abstract

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Topical photodynamic therapy for primary cutaneous B-cell lymphoma: A pilot study

Mori¹,

Campolmi

Mavilia

et al. 2006

Journal of the American Academy of Dermatology

View full text Add to dashboard Cite

show abstract

“…There were several subsequent reports that topical treatment with ALA-PDT can be successfully used for other types of cutaneous T-cell lymphomas [5, 7]; however, there has been no report of ALA-PDT in the treatment of benign cutaneous lymphoid hyperplasia.…”

Section: Discussionmentioning

confidence: 99%

“…Topical ALA-PDT has been used to treat superficial nonmelanoma skin cancers such as squamous cell and basal cell carcinomas, resulting in successful tumor destruction [1, 2]. Thus far, this therapeutic modality has also produced positive results in the treatment of cutaneous T-cell lymphomas including mycosis fungoides [3,4,5,6,7] and cutaneous anaplastic large cell lymphoma [8]. Lymphadenosis benigna cutis (LABC) is a benign cutaneous lymphoid hyperplasia characterized by nodular lesions with dermal infiltration of lymphocytes admixed with histiocytes and occasional plasma cells.…”

Section: Introductionmentioning

confidence: 99%

Successful Treatment of Lymphadenosis benigna cutis with Topical Photodynamic Therapy with Delta-Aminolevulinic Acid

Takeda¹,

Kaneko²,

Harada³

et al. 2005

Dermatology

View full text Add to dashboard Cite

Background: Photodynamic therapy (PDT) using topical δ-aminolevulinic acid (ALA) has been used for nonmelanoma skin cancers, including malignant cutaneous T-cell lymphomas. Moreover, PDT has been tried for benign inflammatory or infectious skin lesions. Objective: To evaluate the effects of ALA-PDT on skin lesions of lymphadenosis benigna cutis (LABC). Patients and Methods: Two 16-year-old females with solitary and infiltrated nodules were treated 5 times with topical ALA-PDT. Results: Both patients responded well and showed dramatic clinical and histopathological improvement without visible scars. Conclusion: The results confirm that topical ALA-PDT is an effective and safe modality for the treatment of LABC, and that such treatment may be cosmetically beneficial.

show abstract

“…Most of these report efficacy of MAL-PDT and ALA-PDT in the treatment of plaque-type (stage I) mycosis fungoides, but decreased efficacy against tumor-type (stage II) mycosis fungoides, and there has been a single report of erosive mycosis fungoides on the face treated successfully with ALA-PDT using red light. 70,[85][86][87][88][89] As is …”

Section: Mal-pdt In Treatment Of Bccmentioning

confidence: 99%

Current Evidence and Applications of Photodynamic Therapy in Dermatology

2015

Journal of the Dermatology Nurses' Association

View full text Add to dashboard Cite

Abstract:In photodynamic therapy (PDT) a photosensitizer -a molecule that is activated by light -is administered and exposed to a light source. This leads both to destruction of cells targeted by the particular type of photosensitizer, and immunomodulation. Given the ease with which photosensitizers and light can be delivered to the skin, it should come as no surprise that PDT is an increasingly utilized therapeutic in dermatology. PDT is used commonly to treat precancerous cells, sun-damaged skin, and acne. It has reportedly also been used to treat other conditions including inflammatory disorders and cutaneous infections. This review discusses the principles behind how PDT is used in dermatology, as well as evidence for current applications of PDT.

show abstract

Topical 5-aminolaevulinic acid photodynamic therapy for tumour-stage mycosis fungoides

Cited by 48 publications

References 8 publications

Topical photodynamic therapy for primary cutaneous B-cell lymphoma: A pilot study

Topical photodynamic therapy for primary cutaneous B-cell lymphoma: A pilot study

Successful Treatment of Lymphadenosis benigna cutis with Topical Photodynamic Therapy with Delta-Aminolevulinic Acid

Current Evidence and Applications of Photodynamic Therapy in Dermatology

Contact Info

Product

Resources

About