Thrombocytopenia in children with malaria–A study from coastal Karnataka, India

Shetty, Guruprasada; Avabratha, K. Shreedhara; Gonsalves, Seema; Dany, A; Sanjeev, B

doi:10.1016/s2222-1808(12)60026-7

Cited by 19 publications

(18 citation statements)

References 5 publications

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“…In this study, 69.4% cases were P.vivax, followed by 21.9% mixed and 9.4% P.falciparum infection. It can be proposed that P.vivax cases are on a rising trend amongst children with greater morbidities (4,5,6). Under-fives were more affected than infants in this study, which is in accordance with previous explanations that, fetal hemoglobin and maternal IgG confer immunity to infants (7,8).…”

Section: Discussionsupporting

confidence: 92%

Clinical and Hematological Changes in Childhood Malaria in India

Chhawchharia¹,

Kolhe²,

George³

et al. 2016

IOSR

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Malaria caused by Plasmodium species is a disease with high morbidity and mortality, especially in children. The changing clinical and blood manifestations of P.falciparum, emerging trends of complications with P.vivax are some of the important issues that merit attention at present in India. The prospective crosssectional study conducted on 170 patients of malaria in Mumbai aimed at studying the clinico-haematological alterations in the disease. Fever and splenomegaly were critical findings in majority of patients so that they may be used for clinical diagnosis of malaria and early institution of therapy. P.vivax was the predominant species with severe thrombocytopenia however anemia was common in P.falciparum infection.Older children were affected more severely than infants with hematological complications, namely anemia and thrombocytopenia. Anemia and thrombocytopenia were common observations while leucocyte count was normal in most patients. After 48 hours of antimalarial treatment, platelet count improved with restoration to normal in majority of patients while anemia worsened in most cases. There was a negative correlation between platelet count and hyperparasitemia. Despite availability of extensive literature on various manifestations of malaria, the evolving nature of the disease mandates continuous revision of existing data.

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Section: Discussionsupporting

confidence: 92%

Clinical and Hematological Changes in Childhood Malaria in India

Chhawchharia¹,

Kolhe²,

George³

et al. 2016

IOSR

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“…Thrombocytopenia is a common finding in several acute infective diseases including malaria 4,5,6 . In our study, thrombocytopenia was present in all types of malaria species which was similar to findings in other Indian studies 7,8 . However, severe thrombocytopenia was more common in falciparum malaria in our study.…”

Section: Discussionsupporting

confidence: 92%

Platelet profile and its correlation to paediatric patients with acute malaria in a tertiary care hospital

Joshi¹,

Gamit

2016

Sri Lanka J Child Health

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“…This is in accordance with 100 % and 86.12 % infestation levels found in 2004 and 2009 from school girls of Ratchaburi Province, Thailand [16] . This tendency has also been reported many authors in different countries like India [36] , Pakistan [27,38,39] , Malaysia[ 32] , Iran [27,40] , Taiwan [41] , Venezuela [42] , Brazil [43] , Egypt [44] , Turkey [45] and Greece [28] .…”

Section: Discussionsupporting

confidence: 73%

“…Akhter et al [37] found that the prevalence of pediculosis was higher in population of ≤15 years old group (22.15 % ) than that in population of [16][17][18][19][20][21][22][23][24][25] years old group (18.33 % ), [26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45] years old group (13.20 % ) and ≥45 years old group (10.0 % ). Also, school children tended to mix more with person of the same age and contact at a school or home were more intimate than at a work place [13] .…”

Section: Discussionmentioning

confidence: 99%