Platelet profile and its correlation to paediatric patients with acute malaria in a tertiary care hospital

Joshi, Gurudutt; Gamit, Deepak

doi:10.4038/sljch.v45i2.8117

Cited by 1 publication

(2 citation statements)

References 8 publications

(8 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The study also observed that PDW 6-10 was more sensitive for PF than PV infection [ 34 ]. This is agreed by other researchers that PDW in the range of 6-10 was a more sensitive indicator for falciparum (82.6%) than vivax (69.5%) malaria [ 47 ].…”

Section: Platelet Indicessupporting

confidence: 88%

“…This is also supported by other studies that MPV > 8 fL showed significant sensitivity of 61.5% with low specificity of 41%. The study also observed that higher MPV (>8 fL) was a more sensitive indicator for PV infection than other plasmodium species, which is similar to a study conducted by Gurudutt and Deepak [ 16 , 34 , 47 ]. There was a strong inverse correlation between platelet counts and MPV.…”

Section: Platelet Indicessupporting

confidence: 87%

See 1 more Smart Citation

Role of Platelet Indices as a Potential Marker for Malaria Severity

Bayleyegn

Asrie

Yalew

et al. 2021

Journal of Parasitology Research

View full text Add to dashboard Cite

Purpose. Platelet parameter alteration such as platelet count and platelet indices are more common than in other blood cell lines due to diverse causative pathophysiological mechanisms in severe malaria infection. In malaria patients, no more studies evaluated platelet indices in relation to disease severity and prognosis. Therefore, this review assessed the current scientific knowledge on the potential role of platelet indices for the diagnostic marker of severe malaria infection. Results. Hence, after reviewing recent literatures, elevation of mean platelet volume and platelet distribution width in addition to decreased plateletcrit and platelet counts is the known potential risk factor associated with warning signs of severe malaria. Thus, thrombocytopenia < 150 × 10 9 / L , MPV ≥ 9.05 fL , and PDW ≥ 14.550 % as well as significantly higher P-LCR and decrease in PCT are shown significant sensitivity and specificity as they are used as diagnostic and prognostic values in severe malaria infection. Conclusion. Platelet indices are useful predictors of malaria severity. Immature platelet fraction (IPF%) is raised in the case of severe malaria, and it was significantly more useful than MPV. Advanced research will further investigate the platelet index abnormality associated with specific age and gender among specific malaria species.

show abstract

Section: Platelet Indicessupporting

confidence: 88%