Three-year clinical comparison of 3-piece AcrySof and SI-40 silicone intraocular lenses

Abstract

The second-generation silicone IOL was equivalent to the 3-piece AcrySof in patient satisfaction, visual function, inflammation, and PCO. The amount of anterior capsule overlap on the IOL may help to explain the study differences.

Lens Epithelial Cell Migration between Posterior Capsule and Intraocular Lens with Variously Finished Posterior Optic Edge and Two Haptic Angulations

“…The 10-degree angulated haptics of the Acrysof may help adhesion to the capsule and contribute to a lower Nd:YAG posterior capsulotomy rate since haptic angulations of many IOLs are 5° ( table 1). Although the acrylic IOL was considered to be better in the prevention of PCO than the conventional silicone IOL [21][22][23], second-generation silicone IOLs with sharp optic edges may come to equal acrylic IOLs as shown in a 2-year study [13] and in our observation.…”

Rate of posterior capsule opacification in eyes with the Akreos intraocular lens

“…Halpern et al 9 report similar findings that, eyes with silicone IOLs were more likely to develop significant PCO leading to Nd:YAG capsulotomy. However, Daynes et al 10 found similar PCO rates with second-generation silicone IOLs and acrylic IOLs. In a study evaluating foreign-body response to IOLs by Hollick et al, 11 silicone IOLs produced significantly higher small-cell and giant-cell counts than the acrylic IOLs, suggesting this could be another factor contributing to lower Nd:YAG rates with acrylic IOLs.…”

Effect of square-edged intraocular lenses on neodymium:YAG laser capsulotomy rates in the United States

“…In a retrospective study with a 3-year follow-up and a prospective randomized study with a 1-year follow-up, this IOL showed excellent PCO performance, potentially reducing national laser capsulotomy rates. 38,39 Also, surveys of members of the American Society of Cataract and Refractive Surgery found a decrease in preference for PMMA IOLs (from 85% in 1993 to 5% in 2002), which were associated with high rates of PCO. 40,41 At the end of the period evaluated, AcrySof IOLs were no longer the only square-edged IOL in use in the U.S.…”