Thermometry in Therapeutic Hyperthermia

Samulski, Thaddeus V.; Fessenden, Peter

doi:10.1007/978-3-642-74636-9_1

Cited by 16 publications

(2 citation statements)

References 68 publications

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“…The use of fiber optic catheter temperature sensors dates back decades across a range of treatment methods [11]–[13]. Probes are fast and accurate, but coverage is limited to the sensor tip and inherently invasive.…”

Section: Introductionmentioning

confidence: 99%

Real-time Microwave Imaging of Differential Temperature for Thermal Therapy Monitoring

Haynes

Stang

Moghaddam

2014

IEEE Trans. Biomed. Eng.

110

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A microwave imaging system for real-time 3D imaging of differential temperature has been developed for the monitoring and feedback of thermal therapy systems. Design parameters are constrained by features of a prototype focused microwave thermal therapy system for the breast, operating at 915 MHz. Real-time imaging is accomplished with a precomputed linear inverse scattering solution combined with continuous Vector Network Analyzer (VNA) measurements of a 36-antenna, HFSS modeled, cylindrical cavity. Volumetric images of differential change of dielectric constant due to temperature are formed with a refresh rate as fast as 1 frame per second and 1°C resolution. Procedures for data segmentation and post-processed S-parameter error-correction are developed. Antenna pair VNA calibration is accelerated by using the cavity as the unknown thru standard. The device is tested on water targets and a simple breast phantom. Differentially heated targets are successfully imaged in cluttered environments. The rate of change of scattering contrast magnitude correlates 1:1 with target temperature.

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Section: Introductionmentioning

confidence: 99%

Real-time Microwave Imaging of Differential Temperature for Thermal Therapy Monitoring

Haynes

Stang

Moghaddam

2014

IEEE Trans. Biomed. Eng.

110

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“…Hence, temperature monitoring needs to be considered as an integral part of every reliable thermotherapy system [31]. In past decades, several methods have been proposed in the literature among which the invasive measurements in tumor-related reference points [7,21,27] and MR-guided thermometry [10,14,32] are currently in clinical use.…”

Section: Introductionmentioning

confidence: 99%

Microwave thermometry with potential application in non-invasive monitoring of hyperthermia

Aram

Beilina

Trefná

2020

Journal of Inverse and Ill-Posed Problems

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Integration of an adaptive finite element method (AFEM) with a conventional least squares method has been presented. As a 3D full-wave forward solver, CST Microwave Studio has been used to model and extract both electric field distribution in the region of interest (ROI) and S-parameters of a circular array consisting of 16 monopole antennas. The data has then been fed into a differential inversion scheme to get a qualitative indicator of how the temperature distribution evolves over a course of the cooling process of a heated object. Different regularization techniques within the Tikhonov framework are also discussed, and a balancing principle for optimal choice of the regularization parameter was used to improve the image reconstruction quality of every 2D slice of the final image. Targets are successfully imaged via proposed numerical methods.

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Technical and Clinical Quality Assurance

Visser

Rhoon

1995

Thermoradiotherapy and Thermochemotherapy

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Thermometry in Therapeutic Hyperthermia

Cited by 16 publications

References 68 publications

Real-time Microwave Imaging of Differential Temperature for Thermal Therapy Monitoring

Real-time Microwave Imaging of Differential Temperature for Thermal Therapy Monitoring

Microwave thermometry with potential application in non-invasive monitoring of hyperthermia

Technical and Clinical Quality Assurance

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