Microwave thermometry with potential application in non-invasive monitoring of hyperthermia

Abstract

Integration of an adaptive finite element method (AFEM) with a conventional least squares method has been presented. As a 3D full-wave forward solver, CST Microwave Studio has been used to model and extract both electric field distribution in the region of interest (ROI) and S-parameters of a circular array consisting of 16 monopole antennas. The data has then been fed into a differential inversion scheme to get a qualitative indicator of how the temperature distribution evolves over a course of the cooling process of a heated object. Different regularization techniques within the Tikhonov framework are also discussed, and a balancing principle for optimal choice of the regularization parameter was used to improve the image reconstruction quality of every 2D slice of the final image. Targets are successfully imaged via proposed numerical methods.

Feasibility Analysis of Theranostic Magnetic Scaffolds for Microwave Monitoring of Hyperthermia Treatment of Bone Tumors

“…Among the many biomedical applications of microwave (MW) diagnostic imaging [47], [48], [49], its use in the framework of thermal therapy looks promising, due to its capability of being a non-invasive, cost effective, fast and reliable strategy [50], [51], [52]. In particular, MW imaging is an approach under investigation for tissues temperature monitoring during hyperthermia [53] and ablation [54].…”