Theoretical analysis of sensitivity enhancement of surface plasmon resonance biosensor with zinc oxide and blue phosphorus/MoS2 heterostructure

Singh, Sachin; Sharma, Anuj K.; Lohia, Pooja; Dwivedi, D. K.

doi:10.1016/j.ijleo.2021.167618

Cited by 50 publications

(28 citation statements)

References 45 publications

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“…Singh et al constructed a SPR sensor with a blue phosphorus (BlueP)/TMDs heterostructure. 174 The BlueP/TMDs heterostructure not only prevents the oxidation of the plasma layer but also provides sufficient excitation energy with gold film charge transfer and robust analyte collection to enhance the proposed SPR sensor performance (Figure 10a). Two-dimensional material heterostructures offer significant advantages over single components.…”

Section: Flexible and Diverse Surface Modification Strategiesmentioning

confidence: 99%

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Review of Interface Modification Based on 2D Nanomaterials for Surface Plasmon Resonance Biosensors

et al. 2022

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Surface plasmon resonance biosensors are drawing attention due to their real-time, label-free, and rapid characteristic. To detect trace biomarkers (ct-DNA, mi-RNA, PD-L1), plasmonic and metal oxide nanoparticles have been utilized for signal amplification and have shown exciting results. To achieve uniform, reproducible, simple, and sensitive sensor interface construction, two-dimensional materials such as graphene and molybdenum sulfide have opened a research upsurge and show a great possibility in the surface plasmon resonance biosensing field due to their unique large specific surface area, excellent in-plane electron transport effect, and singular optical properties. Here, we provide an overview of the recent research progress on two-dimensional materials in the field of surface plasmon resonance biosensors, including the optoelectronic properties of two-dimensional materials, sensitivity enhancement mechanism, and interface construction. Finally, the challenges and development directions of detection sensitivity enhancement are summarized and prospected. Our work will provide a useful platform to expand the further application of two-dimensional materials in surface plasmon resonance biosensors.

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Section: Flexible and Diverse Surface Modification Strategiesmentioning

confidence: 99%

Section: D Nanomaterials For Plasmonic Sensing Applicationsmentioning

confidence: 99%

Review of Interface Modification Based on 2D Nanomaterials for Surface Plasmon Resonance Biosensors

et al. 2022

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“…The detection accuracy of the biosensor was enhanced by using zinc oxide and blue phosphorus molybdenum disulfide heterostructures. The proposed SPR sensor can be practically applied in SPR chips and can detect biomolecules in the visible light range [18]. In medical detection of hemoglobin and blood glucose levels, Mostufa, S. [19] et al introduced graphene coating to SPR sensors and increased the maximum sensitivity to 200 deg/RIU.…”

Section: Introductionmentioning

confidence: 99%

Research on Tunable SPR Sensors Based on WS2 and Graphene Hybrid Nanosheets

et al. 2022

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A prismatic excitation-based affinity biosensor consisting of the prism (BK7), WS2/graphene hybrid nanosheets, and silver (Ag) as the active metal for the surface plasmon resonance is proposed in this present research. The introduction of the transition metal WS2/graphene layer protected the silver substrate and enhanced the adsorption of biomolecules, which facilitated the quality and performance of detection. Here, we improved the detection structure by focusing on the metallic materials, graphene and WS2 film layers, and the thickness of the measured medium on the sensing effect. The results show that the silver film had a more desirable resonance effect, and the design of the symmetric detection structure produced a double resonance peak, and it provides a reference for distributed sensing. Changing the thickness of the detection medium can dynamically adjust the wave vector matching conditions, which gives the sensor a certain tunability. In the bilayer WS2 and monolayer graphene (W = 2, G = 1) configuration, the sensitivity was up to 224 deg/RIU with a quality factor of 96.97 RIU−1, which has potential for clinical analytic and biochemical detecting applications.

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“…Singh et al theoretically analysed a SPR sensor design using zinc oxide and blue phosphorus/ MoS2 heterostructure with CaF2 prism to enhance the sensitivity of the device and obtained highest value of sensitivity as 235 0 /RIU [24]. Wu et al used few layer of black phosphorusgraphene/TMDCs heterostructure to improve the sensitivity of SPR sensor using Ag but maximum sensitivity obtained is 279 0 /RIU [25].…”

Section: Introductionmentioning

confidence: 99%

Comparative study of Au, Al, and Ag metal based SPR sensor using nickel and antimonene to enhance the sensitivity in visible range

Pandey

Singh

Lohia

et al. 2022

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In this simulation work, comparative study of surface plasmon resonance (SPR) based sensor designed with gold (Au), Aluminium (Al), Silver (Ag) are numerically investigated to improve the performance parameter of device using Ni-Antimonene layer in the visible range of light at wavelength of 633nm. In this device configuration, different metals (Ag/Au/Al), a diamagnetic material (Fe2O3), Nickel (Ni) and 2D material Antimonene (Sb) is used with CaF2 glass prism using Kretschmann configuration with angle interrogation method. The angle interrogation method is used to examine the performance of the device. The performance parameters of SPR sensor such as sensitivity, detection accuracy (DA), quality factor (QF) has been calculated. The thickness of metals (Au/Al/Ag) and number of different material thickness has been optimized by using genetic algorithms to improve the performance of device. The present study reveals that Ag metal based SPR Sensor exhibit a higher sensitivity as compared to Al and Au based SPR sensor at 55 nm of thickness. At 55nm thickness of Ag minimum reflectance curve has been obtained in comparison with Au and Al. The studied multilayer configuration of SPR sensor device using different metal Au/Al/Ag with Fe2O3, Ni and Antimonene in presence of glass prism, the maximum sensitivity 3100/RIU is obtained in case of Ag. The sensitivities of Au and Al metals are 660RIU-1, 2040RIU-1 respectively which is less in comparison to Ag metal. The different performance parameter of SPR sensor such as sensitivity, full width at half maximum (FWHM) value, DA, figure of merit (FoM), limit of detection (LoD) is calculated for all three metals but in the case of Ag performance is good compared to Au and Al. The penetration depth (PD) 110.5nm and 3D plot of transverse electric (TM) field intensity have also been plotted. The proposed SPR sensor using Ag metal with highest sensitivity value has capability to detect the different liquid analytes in the field of biosensing application with large uses in biomedical field in visible range.

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Theoretical analysis of sensitivity enhancement of surface plasmon resonance biosensor with zinc oxide and blue phosphorus/MoS2 heterostructure

Cited by 50 publications

References 45 publications

Review of Interface Modification Based on 2D Nanomaterials for Surface Plasmon Resonance Biosensors

Review of Interface Modification Based on 2D Nanomaterials for Surface Plasmon Resonance Biosensors

Research on Tunable SPR Sensors Based on WS2 and Graphene Hybrid Nanosheets

Comparative study of Au, Al, and Ag metal based SPR sensor using nickel and antimonene to enhance the sensitivity in visible range

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