The Precursor to the Hemangioma

Payne, Meredith M.; F, Moyer; Marcks, Kerwin M.; Trevaskis, Allan E.

doi:10.1097/00006534-196607000-00013

Cited by 39 publications

(21 citation statements)

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“…About one third of these tumors appear with premonitory neonatal signs, usually a red macule, blanched spot, pseudoecchymotic stain, or localized telangiectasia. 7,8 More commonly, cutaneous hemangiomas manifest at a median age of 2 weeks. There is rapid growth during the first year of life (proliferating phase), slow regression from 1 to 7 years (involuting phase), and complete regression after 8 year of age (involuted phase).…”

Section: Discussionmentioning

confidence: 99%

Congenital hemangiomas and infantile hemangioma: missing links

Mulliken

Enjolras

2004

Journal of the American Academy of Dermatology

307

205

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Section: Discussionmentioning

confidence: 99%

Congenital hemangiomas and infantile hemangioma: missing links

Mulliken

Enjolras

2004

Journal of the American Academy of Dermatology

307

205

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“…At birth, IH are either absent or present as a precursor lesion. Premonitory marks usually consist of a vasoconstricted patch, a bruise‐like macule, or an erythematous telangiectatic patch . After birth, there is often an early proliferative phase characterized by rapid growth.…”

Section: Clinical Coursementioning

confidence: 99%

Haemangioma: clinical course, complications and management

2013

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Summary Despite their high incidence, most infantile haemangiomas (IH) do not require treatment as they regress spontaneously and most do not leave significant sequelae. For the subset of haemangiomas that require treatment, indications for intervention can be divided into three main categories: ulceration, disfigurement and impairment of function or vital structures. In addition, certain IH have a risk of associated structural anomalies. Given the wide heterogeneity of haemangiomas, deciding which haemangiomas need intervention and when to intervene requires a detailed knowledge of natural history and clinical indicators of increased risk.

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“…1,2 Precursor lesions of IH appear as telangiectatic patches, pink macules resembling capillary malformations, blanched areas, or lesions resembling bruises. [3][4][5][6] Hemangiomas of infancy, unlike other vascular tumors, express glucose transporter (GLUT)-1 protein in the endothelial cells. 7,8 We have observed that there are some newborns with vascular birthmarks that initially appear to be either an IH precursor or resemble capillary malformations, and do not proliferate or show a very limited amount of growth.…”

mentioning

confidence: 99%