The Potency of Flavonoid Compounds in water Extract Gyrinops Versteegii Leaves as Natural Antioxidants Sources

Abstract

Flavonoids can provide antioxidant effects by preventing the formation of ROS, directly capture ROS, protect lipophilic antioxidants and stimulate the increase of enzymatic antioxidants. Flavonoids are phenolic compounds that are widely found in medicinal plants, one of which is Gyrinops versteegii leaves. In this research to determine the potential of flavonoids in water extract Gyrinop versteegii as one source of natural antioxidants was investigated. This research begins with maceration of Gyrinops versteegii leaves with some solvents such as ethyl acetate, ethanol, methanol and water. Each of the extracts obtained measured the total content of Phenol. The extract, which had the highest total phenol content, measured the total flavonoid content and antioxidant capacity. The active extract as antioxidant was further isolated and identified its flavonoid content. Flavonoids obtained measured antioxidant capacity in vitro. Total phenol (mg GAE/100 g) of ethyl acetate extract = 443, ethanol extract =1.510, methanol extract = 6.069 and water extract = 14.979, total flavonoid contens = 2298, 977 mg QE/100 gram, containing phenol, flavonoid, tannin, alkaloid and steroid compounds. Antioxidant capacity with IC50 = 3,45 ppm (5 min.) and 3,05 (60 min.). Identification of isolates with UV-Vis spectroscopy showed 2 absorption bands namely band I at 352 nm and band II at 256 nm. Addition of AlCl3 / HCl shear reagent showed band I undergoing a 2 nm batochromic shift. These results indicate that the resulting flavonoid is suspected to be a flavonoid group of flavonol substituted -OH group at C-5 or 5-hydroxy-flavonol. and its antioxidant capacity or IC50 = 17,14 ppm. These results indicate that the isolated flavonoid has very strong antioxidant activity and is potentially developed as a natural antioxidant.

Diversity of Gyrinops versteegii from several agarwood plantation on Lombok Island (Indonesia) as raw material of Gyrinops tea

“…This morphology character should be added with characters that could be contributed to the diversity of Gyrinops agarwood tea product. Phytochemical character (Parwata et al 2018) and molecular character in the form of DNA fingerprinting (Siburian et al 2017) are two potential additional basis data that could fulfill this requirement. The phytochemical profile had an essential role in determining the variation of agarwood tea products from Aquilaria malaccensis (Batubara et al 2020;Surjanto et al 2019) and Gyrinops versteegii (Wangiyana et al 2021a).…”

A Study on the Antioxidant and Active Compounds of <em>Gardenia jasminoides</em> Ellis (GJE) Leaves Extract

“…The characteristic aromatic ring C=C, was shown by the absorption at the wave number 1528,65 cm -1 and, 1708,04 cm -1 was carbonyl ring stretch C=O . This is a chromophore group that is common in flavonoids in the conjugated bond system (Parwata et al, 2018). Based on the results, the fK isolate was assumed as flavonoid compounds 3,5,7,4 'tetrahydroxy flavonol, and 3,5,7,3,4' penta hydroxy flavonols.…”

Therapeutic Potential of Agarwood in Oral Chronic Inflammatory Diseases Management

“…There is also a flavonoid compound in the agarwood extract that can provide antioxidant effect by preventing the formation of ROS, directly capturing ROS, protecting lipophilic antioxidants and stimulating the increase of enzymatic antioxidants [18]. In addition, different concentrations of agarwood essential oil have scavenging effects on DPPH free radicals, hydroxyl free radicals and superoxide anion free radicals, and with the increase of the concentration of agarwood essential oil, the antioxidant capacity gradually increases, with obvious correlation [19]. The analysis results also showed that both young leaves and mature leaves of agarwood have strong antioxidant activity, and the two kinds of leaves have the same use value in terms of chemical content and antioxidant capacity, which can reduce inflammatory reaction to a certain extent [20].…”