The morphology of the nasal septum in identical twins

Abstract

A comparison was made of the nasal septums of 41 pairs of identical twins to assess the impact of genetic and environmental factors on the formation of deformities of the nasal septum. Deformities of the anterior nasal septum (cartilaginous septum) were present in 22% of all the individuals studied, and in the posterior nasal septum (bony septum), some deformity was present in 74% of the persons studied. The distribution of deformities within pairs suggests that anterior deformities might be of external origin (e.g., traumatic), and posterior deformities may be considered to be part of a normal developmental process of the maxillary complex, where both genetic and epigenetic factors may play a role.

A Prospective Study of Nasal Septal Deformities in Kashmiri Population Attending a Tertiary Care Hospital

“…Differences in the results retrieved from the afore-mentioned studies may be related to the age groups studied. On the other hand, in the study conducted by Kawalsky and Przemyslaw [24] nasal septal deformity was found to be 22.2% in children born by spontaneous delivery but only 3.9% among the infant delivered by caesarean section. In the light of this information, it can be thought that the different results found may be related to different age groups, traumatic factors including birth injury as well as racial factors.…”

“…Subsequent growth of nose accentuates these asymmetries. Combined septal deformity involving all septal components caused by compression across the maxilla regarding to the birth molding theory, while the anterior cartilage deformity of the quadrilateral septal cartilage caused by direct trauma [19][20][21][22][23][24]. Grymer and Melsen (1989) who were able to examine 41 pairs of identical twins suggested that anterior lesions were due to an external cause-trauma where as the posterior lesions due to genetic factors [25].…”

The nasal septum deformities in children and adolescents from Warsaw, Poland

“…According to the research of development of nasal septum in monozygotic twins [18][19][20], the anterior nasal septum deformities are the result of injury while the posterior nasal septum deformities are the consequence of the growth of nasomaxillary complex. In study population, the main factor deciding about the shape of nasal septum was the development of nasomaxillary complex.…”

The relationship between septal deviation and concha bullosa

“…The answer to this question is not clear. According to the theory of Grymer and Melson, [17] posterior septal deviation is accepted as a genetic condition and we believe this may lead to concha bullosa with air flow theory. Is septal deviation the cause and concha bullosa the result?…”