The micronutrient profile of medicinal plant extracts

The level of consumers’ satisfaction with the quality of edible chicken eggs is determined, in particular, by the attractive appearance of the yolks and their content of biologically active substances that have functional properties. Such compounds include carotenoids astaxanthin and lycopene, which can be deposited in the yolks, provide their pigmentation, and as powerful antioxidants, affect the stability of the fatty acid composition of lipids during egg storage. The aim This study aimed mine the effect of supplements of oil extracts of astaxanthin (10, 20, and 30 mg/kg of feed) or lycopene (20, 40, and 60 mg/kg of feed) on the Dion of young hens on the fatty acid composition of the yolks during eggs storage in temperature conditions 4 ±0.5 ℃ and 12 ±0.5 ℃ for 30 days. The experiment used 45 High-Line W36 crossbred laying hens at 24 weeks of age. It was found that the storage temperature of eggs (4 ±0.5 ℃ and 12 ±0.5 ℃) equally affected the fatty acid composition of lipids of egg yolks obtained from laying hens fed lycopene supplements in doses of 20, 40, and 60 mg/kg or astaxanthin in doses of 10, 20 and 30 mg/kg of feed for 30 days. Doses of lycopene from 20 to 60 mg/kg or astaxanthin from 10 to 30 mg/kg in the diet of laying hens contributed to a decrease in egg yolks at both storage temperatures of ω6 PUFA particles: Eicosatetraenoic and 6.9, 12-okadekatrienic acids until their complete disappearance. The addition of astaxanthin to the diet of laying hens reduced and stabilized the ratio of ω3/ω6 PUFA in yolks during egg storage to a greater extent than the addition of lycopene. Storage of lycopene or astaxanthin-enriched edible chicken eggs at 4 ±0.5 °C and 12 ±0.5 °C for 30 days can be used to correct the fatty acid profile of yolk lipids.

Section: Acidsupporting

confidence: 76%

The effect of astaxanthin and lycopene on the content of fatty acids in the yolks of chicken eggs under different storage regimes

Honchar

Iakubchak

Шевченко

et al. 2022

“…The results obtained by us regarding the determination of the cytotoxic effect of disinfectants on the HT-29 cell culture (intestinal epithelium model) (Table 1) show that a clarified solution of perchloric lime caused the destruction of the monolayer and close to 100% cell death in concentrations that correspond to the concentrations of the working solutions of disinfectants and detergents (5000-10000 μl/l) solutions of Biodez, Blanidas, Vircon-S, neochlor, (Figure 1). A series of similar experimental studies were described in scientific works [38], [39], [40], but the researchers used 293-T human kidney (embryonic) with different concentrations that correspond to the concentrations of working solutions of disinfectants and detergents and disinfectants (4500-9000 μl/l) Biodez demonstrates significant cytotoxicity for HT-29 cell culture. Even at a concentration of 20 μl/l, cell survival is only 66.38 ±2.44% of cells (p <0.001).…”

Section: Resultsmentioning

confidence: 99%

“…Various model systems have been created and improved to study all types of toxicity at the cellular level [12], [13].…”

Section: Introductionmentioning

confidence: 99%

The study of the cytotoxic effect of disinfectants

Iakubchak

Adamenko²,

Таран³

et al. 2023

The toxicity of individual disinfectants has been studied in vitro using human cell cultures (HT-29 (epithelial-like cells of colon adenocarcinoma), HEK 293 (human embryonic kidney cells)) to create a model for assessing the toxicity of residual amounts of disinfectants that can enter milk for a person. Standard tests have been used to assess cell viability and amount: methyl tetrazolium (MTT) test, neutral red cell staining (NRP), and sulforhodamine B (SRB) test. Disinfectants have a dose- and time-dependent cytotoxic effect on human cell cultures. IC50avg (concentration of the drug that suppresses a certain cell function by 50%) of disinfectants based on the effect on cell cultures (average value) is Biodez – 117.29 ±14 μl/l, Blanidas – 389.25 ±20.83 μl/l, Virkon-S – 343.04 ±28.04 μl/l, Neochlor – 473.82 ±30.16 μl/l, Phan – 56.71 ±7.05 μl/l, Chlorination – 343.28 ±27.26 μl/l, Chlorinated lime – 117.35 ±9.44 μl/l. Mean toxic doses for cell cultures are lower than the mean lethal dose (based on literature data) for rats and mice by gastric administration. The novelty is that determining the cytotoxicity of disinfectants in vitro using human cell cultures can significantly reduce the number of animals for establishing LD50 during the registration procedure of new agents, making it possible to make preliminary conclusions about the toxicity of substances at the stage of chemical screening, preliminary hygienic regulation, identify target organs of toxic influence.

“…First of all, milky milk is a single suspension that appears with Both of them are the alkaline solution of calcium hydrogen oxide [16]. It also contains inorganic Са(OH)2 in the form of agglomerates that form over time in mixers for "ripening" milk of lime as a result of coagulation of soluble colloidal particles and the so-called hexaquark complexes of calcium hydroxide [17]. As a result of the collapse of the left bubbles in the water-lime suspension, part of the bubbles coalesce with the formation of cumulant streams, which destroy aggregates and complexes of Са(OH)2 [18], [30].…”

Section: Resultsmentioning

confidence: 99%

The use of vapor condensation cavitation to increase the activity of milk of lime in sugar beet production

Жеплінська

Vasyliv

Shynkaruk

et al. 2022

Self Cite

The paper presents research on increasing the activity of milk of lime in beet sugar production using vapor condensation cavitation. The work aimed to develop a rational way of activating milk of lime using the effects of vapor condensation cavitation and its hardware design, substantiating the optimal values of the process parameters. It was established that to increase the activity of milk of lime at a steam potential of 0.18 MPa, an optimal consumption of water vapor using vapor condensation cavitation is required, which is 1 .75 – 2.0% to the weight of the suspension. This is ensured by the action of the combined CaO particles with the bulk of the steam, due to which the Their additional solution is due to the t-plot, which occurs through the boundary layer from the bubbles. As a result, a pre-saturated, water-lime suspension is created, in which the It is the number of dissolved calcium ions. It has been proven that the water vapour-treated suspension is 1.5 times lower It expands and has a volume of sediment of the solid phase in the medium that is 10% larger than that of processed suspension. Such a study is indirect evidence of the increase in the dispersal of these systems after Her husband's work. By increasing the activity of milk of lime, it is possible to increase the effect of cleaning juices at various stages of the technological process and reduce the consumption of limestone for the production of granulated sugar.