The impact of moderate wine consumption on health

Artero, Ana; Artero, Arturo; Tarı́n, Juan J.; Cano, Antonio

doi:10.1016/j.maturitas.2014.09.007

Cited by 156 publications

(113 citation statements)

References 111 publications

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“…Regular alcohol consumption, has been shown to exert a variety of benefits on human health, whereas alcohol abuse is associated with substantial morbidity and mortality [13,14,15]. In particular, it is currently believed that a moderate consumption of certain types of alcoholic beverages, especially red wine, may exert favorable effects on the cardiovascular risk by modulating cellular signaling mechanisms, and inducing biochemical modifications of cellular and plasma components that ultimately decrease the risk of arterial thrombosis and ischemic heart disease [16].…”

Section: Introductionmentioning

confidence: 99%

Alcohol consumption and venous thromboembolism: friend or foe?

Lippi

Mattiuzzi²,

Franchini

2015

Intern Emerg Med

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A light to moderate consumption of certain types of alcoholic beverages may exert a favorable effect on cardiovascular risk, but no conclusive information is available on the putative relationship between alcohol intake and the risk of venous thromboembolism (VTE). We performed an electronic search on Medline and Scopus, using the keywords "venous thromboembolism", "venous thrombosis" and "alcohol", to identify clinical studies linking alcohol intake and VTE risk. The literature search generated 16 studies, 4 of which are case-control, 1 cross-sectional and 11 prospective. Significant reduction of VTE associated with alcohol intake is observed in only 4/16 studies, and in all these the association is only meaningful for a moderate amount of alcohol (i.e., 2-4 glasses). Unlike these trials, two other studies observe that alcohol intake is associated with an increased risk of VTE, whereas the association is insignificant in the remainder. Binge drinking increases the VTE risk in one study but not in another. The consumption of beer is associated with a decreased VTE risk in one study but not in two others. We hence conclude that the relationship between intake of alcoholic beverages and increased or decreased risk of VTE is largely elusive.

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Section: Introductionmentioning

confidence: 99%

Alcohol consumption and venous thromboembolism: friend or foe?

Lippi

Mattiuzzi²,

Franchini

2015

Intern Emerg Med

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“…В ряде эпидемиологических исследований имеются указания на более значимый протективный эффект вина в отношении ССЗ по сравнению с другими спиртными напитками, что обычно объясняют содержанием в нем полифенолов [2,80,81]. Среди полифенолов наибольшее внимание привлекает ресвератрол, что может опреде-ляться его ингибирующим влиянием на стерол-регулиру-ющий протеин SREBP-1c -ключевой транскрипционный фактор липогенеза, а также подавлением оксидативного стресса [82].…”

Section: что предпочтительнее?unclassified

When an enemy becomes a friend. On the benefits of alcohol consumption

Буеверов¹,

Богомолов²

2018

Med. sov.

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Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский университет) 2 Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского ВРАГ, СПОСОБНЫЙ СТАТЬ ДРУГОМ К ВОПРОСУ О ПОЛЬЗЕ АЛКОГОЛЯ В то время как высокие дозы алкоголя являются доказанным фактором риска поражения различных органов и систем, в отношении малых и умеренных доз накоплены противоположные данные. Так, регулярное употребление спиртных напит-ков в небольших количествах уменьшает вероятность развития ишемической болезни сердца, инсульта, сахарного диа-бета 2-го типа, неалкогольной жировой болезни печени, остеопороза и некоторых других заболеваний, а также снижает общую смертность. Малые дозы алкоголя подавляют активность воспаления и перекисного окисления, нормализуют гемокоагуляцию, улучшают липидный профиль, благоприятно влияют на тонус сосудистой стенки и чувствительность тка-ней к инсулину. Наиболее изучены позитивные эффекты вина, что обычно объясняется содержанием в нем полифенолов, в меньшей степени -пива; однако следует учитывать, что в большинстве проведенных исследований фигурировали раз-ные виды спиртных напитков. Таким образом, можно признать нецелесообразным полный запрет на употребление алко-голя лицам без зависимости и специфических органных поражений. Vladimirsky Moscow Regional Research Clinical Institute WHEN AN ENEMY BECOMES A FRIEND. ON THE BENEFITS OF ALCOHOL CONSUMPTIONWhile use of high doses of alcohol is a proven risk factor for various organs and systems, use of small and moderate doses bears evidence of the opposite data. Thus, regularly drinking a small amount of alcoholic drinks could reduce a person's chances of developing coronary heart disease, stroke, type 2 diabetes, non-alcoholic fatty liver disease, osteoporosis and some other diseases, and also reduce overall mortality. Small doses of alcohol suppress the inflammation and peroxidation, normalize hemocoagulation, improve the lipid profile, favourably affect blood vessel tone and the insulin-signaling pathways. Positive effects of wine are the most studied, which is usually explained by the fact that it contains polyphenols, while positive effects of beer are studied to a lesser extent; however, it should be borne in mind that the studies were aimed at different types of alcoholic beverages. Thus, it can be considered inappropriate to completely prohibit the use of alcohol to persons without dependence and specific organ damage.

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“…Piceid hydrolysis during wine fermentation releases resveratrol, which is contained in considerably higher amounts in red wines than in white wines because it is mainly present in the berry skin. Red wine is known to contain 10-fold more phenolic compounds than white wine [1]. Additionally, resveratrol wine levels can also be affected by wine exposure to light [4].…”

Section: Resveratrol and Wine Intakementioning

confidence: 99%

“…Wine is a traditional beverage obtained from grapes that has been associated with both healthy and harmful effects on regular consumers [1]. In this context, the majority of European countries have included wine among their most consumed beverages since ancient times.…”

Section: Introductionmentioning

confidence: 99%

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LC-MS as a Tool to Overcome the Limitations of Self-Reported Dietary Assessments in the Determination of Wine Intake

et al. 2017

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Abstract:The nutritional assessment of individuals is usually performed using highly subjective data collecting tools such as food frequency questionnaires, dietary recalls and food records. However, people are not always capable of recalling all foods (and ingredients) consumed, and in some cases, the intake of specific foods is intentionally omitted. Even though wine is considered positive for cardiovascular status, and is an essential part of Mediterranean culture, individuals may not always report its consumption accurately due to the existence of social preconceptions about alcoholic beverages. In this study, the presence of free resveratrol has been determined in human plasma from 25 Spanish volunteers using liquid chromatography coupled to mass spectrometry (LC-MS). This phenolic compound proved to be useful as a dietary biomarker for wine intake in a known population, and the results were compared with those obtained by self-reported dietary assessments. However, certain limitations must also be taken into account such as inter-individual variations and the type of wine consumed. The LC-MS method was validated for trans-resveratrol determination in human plasma, with an LOD (limit of detection) of 50 ng·mL −1 and an LOQ (limit of quantification) of 150 ng·mL −1 , respectively.

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The impact of moderate wine consumption on health

Cited by 156 publications

References 111 publications

Alcohol consumption and venous thromboembolism: friend or foe?

Alcohol consumption and venous thromboembolism: friend or foe?

When an enemy becomes a friend. On the benefits of alcohol consumption

LC-MS as a Tool to Overcome the Limitations of Self-Reported Dietary Assessments in the Determination of Wine Intake

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