2012
DOI: 10.4269/ajtmh.2012.11-0770
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The History of Dengue Outbreaks in the Americas

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Cited by 351 publications
(277 citation statements)
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References 54 publications
(60 reference statements)
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“…aegypti reinfestation (1971-99) was caused by the failure of eradication programmes leading to increased dispersal of the mosquito and DENV circulation and a corresponding clear increase in the number of outbreaks over the 2000-10 period. During 2010, more than 1.7 million dengue cases were reported, with 50 235 severe cases and 1 185 deaths (Brathwaite et al, 2012). The epidemic seemed to continue extending globally in the following years; in 2015, the total number of suspected or laboratoryconfirmed dengue cases notified to WHO for the Americas, South-East Asia and Western Pacific regions, exceeded three million (Figure A B.1).…”
Section: Dengue Virus Serotypes Health Effects and Epidemicsmentioning
confidence: 99%
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“…aegypti reinfestation (1971-99) was caused by the failure of eradication programmes leading to increased dispersal of the mosquito and DENV circulation and a corresponding clear increase in the number of outbreaks over the 2000-10 period. During 2010, more than 1.7 million dengue cases were reported, with 50 235 severe cases and 1 185 deaths (Brathwaite et al, 2012). The epidemic seemed to continue extending globally in the following years; in 2015, the total number of suspected or laboratoryconfirmed dengue cases notified to WHO for the Americas, South-East Asia and Western Pacific regions, exceeded three million (Figure A B.1).…”
Section: Dengue Virus Serotypes Health Effects and Epidemicsmentioning
confidence: 99%
“…Laboratory studies often reveal thrombocytopenia, a prolonged bleeding time, an elevated prothrombin time, a raised haematocrit, hyperproteinemia and a positive tourniquet test. The liver is often enlarged, soft, and tender (Brathwaite et al, 2012). Several hypotheses have been proposed to explain why DENV now causes devastating epidemics, although it previously caused relatively mild illness.…”
Section: Virus Infection Vectored By Mosquitoesmentioning
confidence: 99%
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“…En América, desde el año 2010, se ha dado un incremento de 4.6 veces en el número de casos de dengue (2). Para Colombia, hasta la semana epidemiológica 17 de 2015, se notificaron 35 796 casos de esta enfermedad, de los cuales 35 318 (98.7%) corresponden a dengue y 478 (1.3%) a DG.…”
Section: Introductionunclassified
“…It was Cuban Dr. Carlos Juan Finlay, working with Dr. Walter Reed, who identified the Ae. Aegypti as the culprit of the yellow fever outbreaks in Haiti and Panama in the 19 th century 10b , The rapid spread of several viri to most of the American continent began around the year 2000 10c . Now a days dengue fever is active in more than 128 countries 11 , chikungunya virus in 40 countries 12 , and the Zika virus in currently 26 countries and rising 13 .…”
Section: Introductionmentioning
confidence: 99%