The effect of pH and fluoride concentration of liquid dentifrices on caries progression

Abstract

The low-F acidic dentifrice combines the desirable characteristics of caries prevention and reduced fluoride intake-for a product to be used by children, regardless their caries status.

Effects of 1450-ppm Fluoride-containing Toothpastes Associated with Boosters on the Enamel Remineralization and Surface Roughness after Cariogenic Challenge

“…27 In addition, previous studies demonstrated that acidic formulations had similar anticaries effect in comparison to neutral formulations. 28,29 In another in vitro study, 30 the surface texture was evaluated after brushing associated with slurries of different pHs. In that study, it was found that brushing associated with basic toothpaste slurries led to a rougher enamel surface, whereas the acidic slurries formed a relatively smoother texture.…”

Review of Fluoride Intake and Appropriateness of Current Guidelines

“…When we think about the best dentifrice that should be recommended to obtain the best risk-benefit relationship, advice might be divergent (i.e., the characteristics of the individual/population should be respected). Both in nonfluoridated (Lima et al 2008) and in fluoridated areas (de Almeida Baldini Cardoso et al 2014), a low-fluoride dentifrice (500–550 ppm) has similar efficacy as the conventional one (1,000–1,100 ppm fluoride) for caries prevention in caries-inactive 2- to 4-y-old children. However, in caries-active children, the conventional dentifrice significantly reduces the progression and net increment of initial caries in comparison with the low-fluoride dentifrice (Lima et al 2008; de Almeida Baldini Cardoso et al 2014).…”

“…Both in nonfluoridated (Lima et al 2008) and in fluoridated areas (de Almeida Baldini Cardoso et al 2014), a low-fluoride dentifrice (500–550 ppm) has similar efficacy as the conventional one (1,000–1,100 ppm fluoride) for caries prevention in caries-inactive 2- to 4-y-old children. However, in caries-active children, the conventional dentifrice significantly reduces the progression and net increment of initial caries in comparison with the low-fluoride dentifrice (Lima et al 2008; de Almeida Baldini Cardoso et al 2014). Thus, the caries risk of the child is an important factor to be taken into account to indicate the type of dentifrice to be used.…”

“…Due to the uncertainties in the literature regarding the anticaries potential of low-fluoride dentifrices, researchers have proposed alterations in their formulations in order that their anticaries potential can be similar to that of a conventional dentifrice, such as pH reduction (de Almeida Baldini Cardoso et al 2014) or phosphate supplementation (Freire et al 2016). Randomized clinical trials evaluating these low-fluoride (500–550 ppm) dentifrices revealed anticaries efficacy similar to that of a conventional dentifrice (1,000–1,100 ppm fluoride) (de Almeida Baldini Cardoso et al 2014; Freire et al 2016). This indicates that they are the best alternative for children, taking into account risk-benefit considerations.…”

“…In the Brazilian market, a low-fluoride liquid acidic dentifrice is available. Clinical trials revealed good results for the prevention of caries and possibly of dental fluorosis (de Almeida Baldini Cardoso et al 2014) because children using this dentifrice had fingernail fluoride concentrations lower than 2 mg/kg (Buzalaf et al 2012).…”