The effect of hydrocarbon ointment containing eel fish (Anguilla bicolor bicolor) and snakehead fish (Channa striata) oil for wound healing in Wistar rats

Sasongko, Heru; Saputro, Bayu Anggoro; Hidayati, Renita Wahyu Nur; Sukmabayu, W S Raka; Sekarjati, Tiara Annisa

doi:10.1063/1.5061899

Cited by 4 publications

(5 citation statements)

References 18 publications

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“…Eel (Anguilla bicolor) is a fish often found in many countries, including Indonesia, Japan, Italy, China, and France (Ahn et al, 2015). However, this fish has not been fully utilized in Indonesia, which can be seen from the public's low consumption of eels (Sasongko et al, 2018). Likewise, around 350 types of sea cucumber are found in Indonesia, making it the biggest producer of sea cucumbers in the world (Lane and Limbong, 2015;Purwati, 2018).…”

Section: Introductionmentioning

confidence: 99%

“…This amount is classified as high so that eels and sea cucumbers have potential activity as an anti-inflammatory. It can be known from previous research that giving ointments containing eel oil can speed up the healing process of a cut wound (Sasongko et al, 2018). It is suspected that the healing process can speed up due to the anti-inflammatory activity of eel oil.…”

Section: Introductionmentioning

confidence: 99%

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Cox-2 inhibition activities of creams containing anguilla bicolor and sea cucumbers extract on croton oil induced inflammation in mice

et al. 2020

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Cox-2 inhibition activities of creams containing anguilla bicolor and sea cucumbers extract on croton oil induced inflammation in mice

et al. 2020

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“…The species has been reported to have bioactive properties such as antiproliferative, antibacterial, and antifungal (Atif et al 2015). M. albus contains vitamins A, B1, B2, B6, C, D, docosahexaenoic acid, eicosapentaenoic acid, and protein (Sasongko et al 2019). The species is rich in protein, amino acids, and fatty acids that are useful as nutrients to accelerate wound healing (Febriyenti et al 2021).…”

Section: Resultsmentioning

confidence: 99%

Animals ethnozoology as traditional medicine in the Dayak Tamambaloh Tribe, Labian Ira'ang Village, Kapuas Hulu District, Indonesia

et al. 2023

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Abstract. Supiandi MI, Syafruddin D, Gandasari A, Mahanal S, Zubaidah S. 2023. Animals ethnozoology as traditional medicine in the Dayak Tamambaloh Tribe, Labian Ira'ang Village, Kapuas Hulu District, Indonesia. Biodiversitas 24: 26-33. The Dayak Tamambaloh community in Labian Ira'ang Village, Kapuas Hulu District, Indonesia, is a community that has traditional knowledge of the use of fauna. However, at this time this knowledge has been reduced or relegated by the times and the use of animals and has never had a written document. This study aimed to obtain the types of animals used by the Dayak Tamambaloh people for treatment. The method used was a survey. Data was collected through literature studies, semi-structured interviews, and field observations. Data on using animals as traditional medicine was obtained from main informants, key informants, and recommendation informants. Data analysis was descriptive and qualitative, including data collection, data reduction, data presentation, and conclusions. The results obtained 13 types of animals in 13 families that are used as traditional medicine by the Tamambaloh Dayak people. The types of animals used in traditional medicine were wanyi (Apis cerana), asu (Canis lupus familiaris), kandalak (Channa striata), panang (Clarias sp.), bunsok (Gekko gecko), dingkawat (Hipposideros larvatus), lati loman (Lumbricus terrestris), tangkiling (Manis javanica), takiung (Sulcospira testudinaria), manuk (Gallus gallus domesticus), ular sawa (Malayopython reticulatus), lundung (Monopterus albus), and beruang (Ursus thibetanus). Animal families used as traditional medicine were Apidae (1 spesies), Canidae (1 spesies), Channidae (1 spesies), Clariidae (1 spesies), Gekkonidae (1 spesies), Hipposideridae (1 spesies), Lumbricidae (1 spesies), Manidae (1 spesies), Pachychilidae (1 spesies), Phasianidae (1 spesies), Pythonidae (1 spesies), Synbranchidae (1 spesies), and Ursidae (1 spesies). The Dayak Tamambaloh people use meat, bile, scales, shells, egg whites, wax, and all parts of animals for traditional medicine.

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“…Fish is one of the possible resources for medication and health supplements (Karsli, 2021). Snakehead (SF) is a freshwater fish that is famous in Asia and often used in the health sector (Virginia et al, 2016, Sahid et al, 2018 because of the protein content in the form of amino acids (Truong et al, 2021), (Pratama et al, 2020), and fatty acids (Sasongko et al, 2018). Farmed snakeheads have become economically important in developing countries such as Indonesia, Malaysia, Thailand, Bangladesh, India, and Vietnam (Bich et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

“…In silico studies stated that fatty acids such as myristic (C14:0), stearic (C18:0), caproidic (C6:0), caprylic (C8:0), pentadecylic (C15:0), and palmitoleic (C16:1 ) received a toxic hazard warning (Elharafi et al, 2021), wherein the free form of these metabolites initiate different harmful activities in cells, particularly on mitochondrial phosphorylation (Schönfeld & Reiser, 2021). Because of the protein content in the form of amino acids (Truong et al, 2021), (Pratama et al, 2020) and fatty acids (Sasongko et al, 2018), some amino acid compounds have been reported for dangerous toxic effects in certain doses. They are methionine, tryptophan, DL-aspartate, histidine, tyrosine, phenylalanine, cystine, leucine, valine, isoleucine, glycine, asparagine, arginine, L-aspartate, lysine, threonine, and glutamate (Samuels, 2020).…”

Section: Introductionmentioning

confidence: 99%

Oral acute and subchronic (28-day) toxicity studies of snakehead fish (Channa striata)

Sasongko

2022

Indonesian J Pharm

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Food and drug control authorities in each country have issued warnings about the toxic effect potential of using commonly consumed traditional medicines. The safety assurance, standardization, and market regulation of herbal medicines being sold need to be determined. This study's goal is to investigate the acute and subchronic toxicity of cold-processed snakehead fish (Channa striata) flesh. In-vivo rats models were given dosages of 350, 1400, and 5600 mg/kg processed snakehead fish (SF) and were monitored for toxic symptoms and mortality for 14 days. Meanwhile, regarding subchronic toxicity, doses of 350, 700, and 1400 mg/kg SF were administered orally for 28 days. Afterward, the animal subjects were sacrificed for histopathological, hematological, and biochemical examinations. There were no evidence of toxicity or mortality in rats during the acute examination, which lasted 14 days. The subchronic toxicity results showed no significant changes in most of the hematological, biochemical, and histological profiles of the organs. Some changes observed in blood biochemistry and relative organ weight were assumed as a temporary effect and not a sign of toxicity. The overall results showed that the SF was non-toxic up to 1400 mg/kg, which can be considered a safe dose for the application of health supplement raw materials.

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The effect of hydrocarbon ointment containing eel fish (Anguilla bicolor bicolor) and snakehead fish (Channa striata) oil for wound healing in Wistar rats

Cited by 4 publications

References 18 publications

Cox-2 inhibition activities of creams containing anguilla bicolor and sea cucumbers extract on croton oil induced inflammation in mice

Cox-2 inhibition activities of creams containing anguilla bicolor and sea cucumbers extract on croton oil induced inflammation in mice

Animals ethnozoology as traditional medicine in the Dayak Tamambaloh Tribe, Labian Ira'ang Village, Kapuas Hulu District, Indonesia

Oral acute and subchronic (28-day) toxicity studies of snakehead fish (Channa striata)

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