The colovesical fistula in congenital pouch colon: a histologic study

Chadha, Ritu; Agarwal, Kiran; Choudhury, Subhasis Roy; Debnath, Pinaki Ranjan

doi:10.1016/j.jpedsurg.2008.05.021

Cited by 5 publications

(4 citation statements)

References 11 publications

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“…There have been a few studies in relation to the histopathology of CPC: four on the pouch [9][10][11][12] and 1 on the colovesical fistula [13] . Histopathology and IHC were performed on all 5 types of CPC.…”

Section: Discussionmentioning

confidence: 99%

“…Chadha [13], 2008 6 1, 2 H&E Aganglionosis in muscle layer, submucosal and subserosal fibrosis, thickness of muscle layer suggestive of internal sphincter.…”

Section: Disclosure Statementmentioning

confidence: 99%

“…on the functional outcome of CPC surgery and a paucity of literature on the histopathological aspects of CPC [4,[7][8][9][10][11][12][13] . To the best of our knowledge, immunohistochemical (IHC) assessment has not yet been attempted and there is no literature available on this.…”

mentioning

confidence: 99%

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Histopathological and Immunohistochemical Findings in Congenital Pouch Colon: A Prospective Study

Udawat¹,

Nunia²,

Mathur³

et al. 2017

Pathobiology

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Background: There is a paucity of literature on the histopathological aspects of congenital pouch colon (CPC) and immunohistochemical (IHC) assessment has not been reported. So we planned to study the histopathological and IHC findings within the spectrum of CPC and compare the findings with the normal colon. Methods: This is a descriptive prospective study on CPC patients. There were 49 cases of CPC (42 males and 7 females) and 13 controls. Histological examination was done using hematoxylin and eosin and Masson trichrome stain. IHC analysis was done with actin, myosin, and desmin antibodies, and neuron-specific enolase and S100 markers for counting ganglionic cells. Results: Histologically, congestion, edema and hemorrhage were seen in mucosa, submucosa, and serosa. Muscle layers were disrupted and divided into bands. An additional muscle coat inside of the muscularis propria was seen in CPC types 1 and 2. Mature ganglionic cells were reduced and muscle layers showed reduced and patchy positivity for smooth muscle actin, myosin, and desmin compared to a normal colon. Conclusions: Histopathological and IHC findings suggest that CPC has distinct defects in the neuromusculature.

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Section: Discussionmentioning

confidence: 99%

“…Chadha [13], 2008 6 1, 2 H&E Aganglionosis in muscle layer, submucosal and subserosal fibrosis, thickness of muscle layer suggestive of internal sphincter.…”

Section: Disclosure Statementmentioning

confidence: 99%

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Histopathological and Immunohistochemical Findings in Congenital Pouch Colon: A Prospective Study

Udawat¹,

Nunia²,

Mathur³

et al. 2017

Pathobiology

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“…Часто у дівчат є спільна фістула в піхву і міхур (колоклоакальна фістула). ВТМ має дуже коротку брижу зі слабо вираженими судинними аркадами, інколи брижа відсутня і судини розпластані на самому мішку [2,6,11].…”

Section: вступunclassified

Rare Colorectal Malformations in Newborns. Literature Review and Own Observations

Fofanov¹,

Fofanov²,

Yurtseva³

2021

Neonatol. hìr. perinat. med.

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The article presents literature data andown observations of some rare congenital malformationsof the colorectal area in newborns that require surgicaltreatment. These are defects such as congenital pouch colonand congenital segmental dilatation of the colon. Thereare isolated cases of birth of children with these defectsin European countries and North America. They are morecommon in Asian countries, especially in India. Diagnosisand surgical correction of such congenital malformationscause difficulties associated with insufficient awarenessof pediatric surgeons, neonatologists, pediatricians aboutthis pathology. Data is presented on clinical manifestations,antenatal and postnatal diagnosis and treatment tactics, aswell as the histopathological structure of the affected colonin these defects.The analysis of literature data and the presented clinicalobservations of congenital pouch colon and congenitalsegmental dilatation of the colon in newborns indicate thepossibility of their antenatal and preoperative diagnosis.It is concluded that children with anorectal malformationsand Hirschsprung's disease require a thorough differentialdiagnosis with congenital pouch colon and segmentaldilatation of the colon, as the tactics of their surgicalcorrection significantly differ from the treatment tacticsof common anorectal malformations and Hirschsprung'sdisease surgical management.

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