Background: There is a paucity of literature on the histopathological aspects of congenital pouch colon (CPC) and immunohistochemical (IHC) assessment has not been reported. So we planned to study the histopathological and IHC findings within the spectrum of CPC and compare the findings with the normal colon. Methods: This is a descriptive prospective study on CPC patients. There were 49 cases of CPC (42 males and 7 females) and 13 controls. Histological examination was done using hematoxylin and eosin and Masson trichrome stain. IHC analysis was done with actin, myosin, and desmin antibodies, and neuron-specific enolase and S100 markers for counting ganglionic cells. Results: Histologically, congestion, edema and hemorrhage were seen in mucosa, submucosa, and serosa. Muscle layers were disrupted and divided into bands. An additional muscle coat inside of the muscularis propria was seen in CPC types 1 and 2. Mature ganglionic cells were reduced and muscle layers showed reduced and patchy positivity for smooth muscle actin, myosin, and desmin compared to a normal colon. Conclusions: Histopathological and IHC findings suggest that CPC has distinct defects in the neuromusculature.
Primary squamous cell carcinoma (SCC) of renal pelvis is a rare neoplasm. A 75-year old male presented with history of chronic dull aching pain in left flank region for last 10-years with history of left pyelolithotomy about 30-years back. After proper workup, large calculus with heterogeneous density mass detected in nonfunctioning left kidney. After radical nephrectomy, histopathological examination revealed squamous cell carcinoma of renal pelvis. SCC should be suspected in a patient with long history of renal calculous and associated mass in non functioning kidney.
Cysticercosis is a parasitic infection caused by Cysticercus cellulosae, the larval stage of Taenia Solium. It is present world-wide, but more prevalent in developing regions like South America, Africa, South-East Asia and Eastern Europe due to poor environmental sanitation. The common sites are skeletal muscle, subcutaneous tissue, brain and eye. Breast is an uncommon site and diagnosis is usually incidental. Only a few cases have been reported, so far. Several diagnostic tools such as radiologic imaging, serology and immunologic detection are being used but the gold standard remains the demonstration of the parasitic larva by FNAC or histopathology.
Here , we report an unusual case of cysticercosis in breast that was diagnosed o by Fine needle aspiration cytology.
KEY WORDS: Cysticercosis, FNAC, Breast
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