The 32P test and other methods in the diagnosis of intraocular tumours

Dijk, René André Van

doi:10.1007/bf00174102

Cited by 17 publications

(4 citation statements)

References 77 publications

(79 reference statements)

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“…According to Van Dijk, the differences in 32 P uptake are due to the mitotic activity of the tumor. 13 In the present analysis, the mitotic count was a highly significant prognostic factor (PϽ.001) but did not correlate with the result of the 32 P uptake test. This confirmed the finding of McLean and Shields, 21 who also could not show a significant correlation between 32 P uptake and the mitotic count.…”

Section: Commentcontrasting

confidence: 58%

Prognostic Value of the Disodium Phosphate 32P Uptake Test in Uveal Melanoma

Overkleeft

Zuidervaart²,

Hurks³

et al. 2003

Arch Ophthalmol

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Section: Commentcontrasting

confidence: 58%

Prognostic Value of the Disodium Phosphate 32P Uptake Test in Uveal Melanoma

Overkleeft

Zuidervaart²,

Hurks³

et al. 2003

Arch Ophthalmol

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“…Until now great improvements in the diagnosis of malignant melanomas of the eye in the last 20 years have been fluoresceinangiography in case of clear media (Norton et al 1964), A-and B-ultrasonography (Coleman et al 1973) and 3zP-test (van Dijk 1978;Brandt et al 1980). Although a high diagnostic reliability has been obtained at these centers of ultrasonography (-96%) and 32P-test (95%).…”

Section: Discussionmentioning

confidence: 99%

Computerized Tomography of Malignant Melanomas of the Choroid

Alsbirk

Halaburt

1983

Acta Ophthalmologica

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Twelve histologically verified choroidal melanomas, 15 normal fellow eyes and 4 simulating lesions (vitreous haemorrhage, choroidal haemorrhage, retinal detachment and choroidal detachment) were CT-scanned before and after intravenous contrast media (maximal attenuation in the tumours were estimated from a computerized curve corresponding to a line placed from the center of the eye, through the tumour to the outside of the bulb). The melanomas showed significantly higher precontrast attenuation (54 HU) than the control eyes (17 HU) measured in symmetrical points. Enhancement was registered in all the tumours (mean = 22 HU, P less than 0.01), but not in the control eyes. Among the simulating lesions, the retinal detachment enhanced after contrast. Indications for CT-scan of intraocular processes are diagnostic doubt in opaque media and suspected extrabulbar extension. A patient with verified, disciform organised subretinal haemorrhage scanned after the primary series showed contrast enhancement comparable to the malignant melanoma series. Also 'CT-positive' tumour eyes have to be observed over a period.

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“…Since then many authors have published mostly good results with high accuracy and negligible side-effects, and this test has become a widely accepted diagnostic procedure (Correns et al, 1961;van Dijk, 1978;Goldberg et al, 1980;Lommatzsch andGuntermann, 1967, 1971;Lommatzsch, 1977;McLean and Shields, 1978;Shields, 1980). Since then many authors have published mostly good results with high accuracy and negligible side-effects, and this test has become a widely accepted diagnostic procedure (Correns et al, 1961;van Dijk, 1978;Goldberg et al, 1980;Lommatzsch andGuntermann, 1967, 1971;Lommatzsch, 1977;McLean and Shields, 1978;Shields, 1980).…”

Section: Introductionmentioning

confidence: 99%

The reliability of radioactive phosphorus (32P) in the diagnosis of intraocular tumors; experience with 912 patients

et al. 1984

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The 32P uptake test used in the differential diagnosis of 912 cases yielded an accuracy rate of 94.82% for intraocular lesions behind the equator, and 85.15% for lesions of the anterior uvea. The highest error rate occurred in patients with suspected tumors of the iris and ciliary body. It seems advisable to take a 40% difference on the uptake as the limit between a positive or negative test result.

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The 32P test and other methods in the diagnosis of intraocular tumours

Cited by 17 publications

References 77 publications

Prognostic Value of the Disodium Phosphate 32P Uptake Test in Uveal Melanoma

Prognostic Value of the Disodium Phosphate 32P Uptake Test in Uveal Melanoma

Computerized Tomography of Malignant Melanomas of the Choroid

The reliability of radioactive phosphorus (32P) in the diagnosis of intraocular tumors; experience with 912 patients

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